Resveratrol: A double-edged sword in health benefits

B Salehi, AP Mishra, M Nigam, B Sener, M Kilic… - Biomedicines, 2018 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

Relationship between oxidative stress, ER stress, and inflammation in type 2 diabetes: the battle continues

E Burgos-Morón, Z Abad-Jiménez… - Journal of clinical …, 2019 - mdpi.com
Type 2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia and insulin
resistance in which oxidative stress is thought to be a primary cause. Considering that …

The interactions between polyphenols and microorganisms, especially gut microbiota

M Makarewicz, I Drożdż, T Tarko, A Duda-Chodak - Antioxidants, 2021 - mdpi.com
This review presents the comprehensive knowledge about the bidirectional relationship
between polyphenols and the gut microbiome. The first part is related to polyphenols' …

Antidiabetic potential of medicinal plants and their active components

B Salehi, A Ata, N V. Anil Kumar, F Sharopov… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus is one of the major health problems in the world, the incidence and
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …

Beneficial effects of adiponectin on glucose and lipid metabolism and atherosclerotic progression: mechanisms and perspectives

H Yanai, H Yoshida - International journal of molecular sciences, 2019 - mdpi.com
Circulating adiponectin concentrations are reduced in obese individuals, and this reduction
has been proposed to have a crucial role in the pathogenesis of atherosclerosis and …

Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases

AE Kane, DA Sinclair - Circulation research, 2018 - Am Heart Assoc
The sirtuin family of nicotinamide adenine dinucleotide–dependent deacylases (SIRT1–7)
are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and …

Resveratrol in treating diabetes and its cardiovascular complications: a review of its mechanisms of action

M Su, W Zhao, S Xu, J Weng - Antioxidants, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most prevalent chronic diseases worldwide. High
morbidity and mortality caused by DM are closely linked to its complications in multiple …

[HTML][HTML] Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A …

W Mahjabeen, DA Khan, SA Mirza - Complementary therapies in medicine, 2022 - Elsevier
Objective The objective was to determine the effects of resveratrol supplementation on
glucose homeostasis, oxidative stress, inflammation and microRNAs expression in patients …

Health benefits of resveratrol administration

S Galiniak, D Aebisher… - Acta biochimica …, 2019 - abp.ptbioch.edu.pl
Resveratrol is a polyphenol that is abundant in grape skin and seeds. Food sources of
resveratrol include wine, berries, and peanuts. This compound has many properties …

Resveratrol, metabolic syndrome, and gut microbiota

A Chaplin, C Carpéné, J Mercader - Nutrients, 2018 - mdpi.com
Resveratrol is a polyphenol which has been shown to have beneficial effects on metabolic
syndrome-related alterations in experimental animals, including glucose and lipid …