Role of endoplasmic reticulum stress in drug‐induced toxicity

F Foufelle, B Fromenty - Pharmacology research & …, 2016 - Wiley Online Library
Drug‐induced toxicity is a key issue for public health because some side effects can be
severe and life‐threatening. These adverse effects can also be a major concern for the …

Intralesional bleomycin injections for vascular malformations: a systematic review and meta-analysis

SER Horbach, IM Rigter, JHS Smitt… - Plastic and …, 2016 - journals.lww.com
Background: Vascular malformations are congenital anomalies of the vascular system.
Intralesional bleomycin injections are commonly used to treat vascular malformations …

Technologies for Targeted RNA Degradation and Induced RNA Decay

S Mikutis, GJL Bernardes - Chemical Reviews, 2024 - ACS Publications
The vast majority of the human genome codes for RNA, but RNA-targeting therapeutics
account for a small fraction of approved drugs. As such, there is great incentive to improve …

The interaction of the metallo-glycopeptide anti-tumour drug bleomycin with DNA

V Murray, JK Chen, LH Chung - International journal of molecular …, 2018 - mdpi.com
The cancer chemotherapeutic drug, bleomycin, is clinically used to treat several neoplasms
including testicular and ovarian cancers. Bleomycin is a metallo-glycopeptide antibiotic that …

Synthesis and characterization of two new mixed‐ligand Cu (II) complexes of a tridentate NN'O type Schiff base ligand and N‐donor heterocyclic co‐ligands: In vitro …

L Ghasemi, M Behzad, A Khaleghian… - Applied …, 2022 - Wiley Online Library
Two new mixed‐ligand complexes with general formula [Cu (SB)(L')] ClO4 (1 and 2) were
synthesized and characterized by different spectroscopic and analytical techniques …

[HTML][HTML] A new approach for the treatment of bleomycin-induced rat pulmonary injury by combined protein fraction of major royal jelly protein 2 and its isoform X1

NH Habashy, SA Olleak, MM Abu-Serie… - Biomedicine & …, 2023 - Elsevier
Nowadays, royal jelly (RJ) has gained great interest as a functional food due to its valuable
pharmacological effects. We investigated the therapeutic potency of combined protein …

Drug Repurposing of Selected Antibiotics: An Emerging Approach in Cancer Drug Discovery

N Bano, S Parveen, M Saeed, S Siddiqui… - ACS …, 2024 - ACS Publications
Drug repurposing is a method of investigating new therapeutic applications for previously
approved medications. This repurposing approach to “old” medications is now highly …

Modeling the risk of radiation-induced lung fibrosis: Irradiated heart tissue is as important as irradiated lung

L Cella, V D'Avino, G Palma, M Conson, R Liuzzi… - Radiotherapy and …, 2015 - Elsevier
Purpose We used normal tissue complication probability (NTCP) modeling to explore the
impact of heart irradiation on radiation-induced lung fibrosis (RILF). Materials and methods …

The treatment of canine mast cell tumours with electrochemotherapy with or without surgical excision

R Lowe, A Gavazza, JA Impellizeri… - Veterinary and …, 2017 - Wiley Online Library
To describe the results of electrochemotherapy (ECT) in dogs with mast cell tumours (MCTs)
either as first line therapy or as an adjuvant to surgery. The treatment combines …

[HTML][HTML] Effects of plant extracts and bioactive compounds on attenuation of bleomycin-induced pulmonary fibrosis

S Hosseini, M Imenshahidi, H Hosseinzadeh… - Biomedicine & …, 2018 - Elsevier
Introduction Bleomycin (BLM) is a chemotherapeutic agent that is used in the management
of some human cancers such as lymphomas and squamous cell carcinomas. The major …