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Dendritic cells in cancer immunology
TL Murphy, KM Murphy - Cellular & molecular immunology, 2022 - nature.com
The clinical success of immune checkpoint therapy (ICT) has produced explosive growth in
tumor immunology research because ICT was discovered through basic studies of immune …
tumor immunology research because ICT was discovered through basic studies of immune …
Dendritic cells revisited
Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, sha** adaptive and innate immunity. Over the years, a …
communicate it to other leukocytes, sha** adaptive and innate immunity. Over the years, a …
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles
Resident macrophages orchestrate homeostatic, inflammatory, and reparative activities. It is
appreciated that different tissues instruct specialized macrophage functions. However …
appreciated that different tissues instruct specialized macrophage functions. However …
[HTML][HTML] Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease
Mononuclear phagocytes (MNPs) encompass dendritic cells, monocytes, and macrophages
(MoMac), which exhibit antimicrobial, homeostatic, and immunoregulatory functions. We …
(MoMac), which exhibit antimicrobial, homeostatic, and immunoregulatory functions. We …
[HTML][HTML] Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors
Conventional dendritic cells (cDCs) are professional antigen-presenting cells that control the
adaptive immune response. Their subsets and developmental origins have been intensively …
adaptive immune response. Their subsets and developmental origins have been intensively …
[HTML][HTML] Transcriptional basis of mouse and human dendritic cell heterogeneity
CC Brown, H Gudjonson, Y Pritykin, D Deep… - Cell, 2019 - cell.com
Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …
their unique ability to initiate T cell responses and direct their differentiation into effector …
Origin and heterogeneity of tissue myeloid cells: a focus on GMP-derived monocytes and neutrophils
Myeloid cells are a significant proportion of leukocytes within tissues, comprising
granulocytes, monocytes, dendritic cells, and macrophages. With the identification of various …
granulocytes, monocytes, dendritic cells, and macrophages. With the identification of various …
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …
development over recent decades. However, this field is currently in a state of flux toward …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
[HTML][HTML] Progenitors of distinct lineages shape the diversity of mature type 2 conventional dendritic cells
Conventional dendritic cells (cDC) are antigen-presenting cells comprising cDC1 and cDC2,
responsible for priming naive CD8+ and CD4+ T cells, respectively. Recent studies have …
responsible for priming naive CD8+ and CD4+ T cells, respectively. Recent studies have …