NLR receptors in plant immunity: making sense of the alphabet soup

MP Contreras, D Lüdke, H Pai, AA Toghani… - EMBO …, 2023 - embopress.org
Plants coordinately use cell‐surface and intracellular immune receptors to perceive
pathogens and mount an immune response. Intracellular events of pathogen recognition are …

The NLR family of innate immune and cell death sensors

B Sundaram, RE Tweedell, SP Kumar, TD Kanneganti - Immunity, 2024 - cell.com
Nucleotide-binding oligomerization domain (NOD)-like receptors, also known as nucleotide-
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …

New biochemical principles for NLR immunity in plants

J Chai, W Song, JE Parker - Molecular Plant-Microbe …, 2023 - Am Phytopath Society
While working for the United States Department of Agriculture on the North Dakota
Agricultural College campus in Fargo, North Dakota, in the 1940s and 1950s, Harold H. Flor …

EVO-MPMI: from fundamental science to practical applications

S Schornack, S Kamoun - Current Opinion in Plant Biology, 2023 - Elsevier
In the unending coevolutionary dance between plants and microbes, each player impacts
the evolution of the other. Here, we provide an overview of the burgeoning field of …

The NRC0 gene cluster of sensor and helper NLR immune receptors is functionally conserved across asterid plants

T Sakai, MP Contreras, C Martinez-Anaya… - The Plant …, 2024 - academic.oup.com
Nucleotide-binding domain and leucine-rich repeat-containing receptor (NLR) proteins can
form complex receptor networks to confer innate immunity. An NLR-REQUIRED FOR CELL …

Allelic variation in the Arabidopsis TNL CHS3/CSA1 immune receptor pair reveals two functional cell-death regulatory modes

Y Yang, NH Kim, V Cevik, P Jacob, L Wan, OJ Furzer… - Cell host & …, 2022 - cell.com
Some plant NLR immune receptors are encoded in head-to-head" sensor-executor" pairs
that function together. Alleles of the NLR pair CHS3/CSA1 form three clades. The clade 1 …

Helper NLRs Nrc2 and Nrc3 act codependently with Prf/Pto and activate MAPK signaling to induce immunity in tomato

N Zhang, J Gan, L Carneal… - The Plant …, 2024 - Wiley Online Library
Plant intracellular immune receptors, primarily nucleotide‐binding, leucine‐rich repeat
proteins (NLRs), detect pathogen effector proteins and activate NLR‐triggered immunity …

Evolutionary and immune‐activating character analyses of NLR genes in algae suggest the ancient origin of plant intracellular immune receptors

XY Feng, Q Li, Y Liu, YM Zhang, ZQ Shao - The Plant Journal, 2024 - Wiley Online Library
Nucleotide‐binding leucine‐rich repeat (NLR) proteins are crucial intracellular immune
receptors in plants, responsible for detecting invading pathogens and initiating defense …

NRC immune receptor networks show diversified hierarchical genetic architecture across plant lineages

FJ Goh, CY Huang, L Derevnina, CH Wu - The Plant Cell, 2024 - academic.oup.com
Plants' complex immune systems include nucleotide-binding domain and leucine-rich repeat-
containing (NLR) proteins, which help recognize invading pathogens. In solanaceous …

Disentangling the complex gene interaction networks between rice and the blast fungus identifies a new pathogen effector

Y Sugihara, Y Abe, H Takagi, A Abe, M Shimizu… - PLoS …, 2023 - journals.plos.org
Studies focused solely on single organisms can fail to identify the networks underlying host–
pathogen gene-for-gene interactions. Here, we integrate genetic analyses of rice (Oryza …