Axial pharmaceutical properties of liposome in cancer therapy: Recent advances and perspectives
Abstract Evaluation of axial properties including preparation, surface functionalization, and
pharmacokinetics for delivery of pharmacologically active molecules and genes lead to …
pharmacokinetics for delivery of pharmacologically active molecules and genes lead to …
A review on various analytical methods for determination of anthracyclines and their metabolites as anti–cancer chemotherapy drugs in different matrices over the last …
Y Pashaei, M Mehrabi, M Shekarchi - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Anthracyclines (ANT), belong to a group of antineoplastic drugs, are commonly used as
chemotherapeutic agents in the treatment of various cancers. During the past decade, the …
chemotherapeutic agents in the treatment of various cancers. During the past decade, the …
[HTML][HTML] In vitro stability and content release properties of phosphatidylglyceroglycerol containing thermosensitive liposomes
M Hossann, M Wiggenhorn, A Schwerdt… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Recently, we reported that 1, 2-dipalmitoyl-sn-glycero-3-phosphoglyceroglycerol (DPPGOG)
prolongs the circulation time of thermosensitive liposomes (TSL). Since the only TSL …
prolongs the circulation time of thermosensitive liposomes (TSL). Since the only TSL …
Human carbonyl reductases
P Malátková, E Maser, V Wsól - Current drug metabolism, 2010 - ingentaconnect.com
Enzymatic carbonyl reduction means the formation of a hydroxy function out of a ketone or
aldehyde moiety and applies for the metabolism of physiological (endogenous) or …
aldehyde moiety and applies for the metabolism of physiological (endogenous) or …
Method of hyperthermia and tumor size influence effectiveness of doxorubicin release from thermosensitive liposomes in experimental tumors
L Willerding, S Limmer, M Hossann, A Zengerle… - Journal of Controlled …, 2016 - Elsevier
Systemic chemotherapy of solid tumors could be enhanced by local hyperthermia (HT) in
combination with thermosensitive liposomes (TSL) as drug carriers. In such an approach …
combination with thermosensitive liposomes (TSL) as drug carriers. In such an approach …
Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by …
A Guerci, JL Merlin, N Missoum, L Feldmann… - 1995 - ashpublications.org
To evaluate the clinical relevance of multidrug resistance (MDR) phenotype, the intracellular
daunorubicin accumulation (IDA) and P-glycoprotein (P-gp) expression were investigated in …
daunorubicin accumulation (IDA) and P-glycoprotein (P-gp) expression were investigated in …
AKR1B10 induces cell resistance to daunorubicin and idarubicin by reducing C13 ketonic group
L Zhong, H Shen, C Huang, H **g, D Cao - Toxicology and applied …, 2011 - Elsevier
Daunorubicin, idarubicin, doxorubicin and epirubicin are anthracyclines widely used for the
treatment of lymphoma, leukemia, and breast, lung, and liver cancers, but tumor resistance …
treatment of lymphoma, leukemia, and breast, lung, and liver cancers, but tumor resistance …
Inherited variation in OATP1B1 is associated with treatment outcome in acute myeloid leukemia
Using broad interrogation of clinically relevant drug absorption, distribution, metabolism, and
excretion (ADME) genes on the DMET platform, we identified a genetic variant in SLCO1B1 …
excretion (ADME) genes on the DMET platform, we identified a genetic variant in SLCO1B1 …
Pharmacokinetics of liposomal daunorubicin (DaunoXome) during a phase I-II study in children with relapsed acute lymphoblastic leukaemia
R Bellott, A Auvrignon, T Leblanc, Y Pérel… - Cancer chemotherapy …, 2001 - Springer
Abstract Purpose: The pharmacokinetics of DaunoXome were studied during a multicentric
phase I-II study performed in children suffering from relapsed acute lymphoblastic leukaemia …
phase I-II study performed in children suffering from relapsed acute lymphoblastic leukaemia …
Carbonyl reduction of naltrexone and dolasetron by oxidoreductases isolated from human liver cytosol
U Breyer-Pfaff, K Nill - Journal of pharmacy and pharmacology, 2004 - academic.oup.com
The opioid receptor antagonist naltrexone and the antiemetic 5-HT3 receptor antagonist
dolasetron are ketonic drugs that are efficiently reduced to their corresponding alcohols in …
dolasetron are ketonic drugs that are efficiently reduced to their corresponding alcohols in …