New insight into umami receptor, umami/umami-enhancing peptides and their derivatives: A review

J Zhang, D Sun-Waterhouse, G Su, M Zhao - Trends in Food Science & …, 2019 - Elsevier
Background The structure and mechanism of umami taste receptor remain largely unclear,
thus, far more research is necessary to increase the knowledge of tasty modalities …

Therapeutic potential of ectopic olfactory and taste receptors

SJ Lee, I Depoortere, H Hatt - Nature Reviews Drug Discovery, 2019 - nature.com
Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …

Identification and taste characteristics of novel umami and umami-enhancing peptides separated from peanut protein isolate hydrolysate by consecutive …

J Zhang, M Zhao, G Su, L Lin - Food Chemistry, 2019 - Elsevier
Six novel peptides were separated from peanut protein isolate hydrolysate (PPIH) using
ethanol precipitation and gel chromatography, and identified as DQR, NNP, EGF, EDG …

Sweet, umami and bitter taste receptors: State of the art of in silico molecular modeling approaches

G Spaggiari, A Di Pizio, P Cozzini - Trends in Food Science & Technology, 2020 - Elsevier
Background The human taste experience is the result of five basic taste qualities, namely
sweet, salty, bitter, sour and umami. Sweet, bitter, and umami are mediated by G protein …

[HTML][HTML] Protein-and peptide-based biosensors in artificial olfaction

AJM Barbosa, AR Oliveira, ACA Roque - Trends in biotechnology, 2018 - cell.com
Animals' olfactory systems rely on proteins, olfactory receptors (ORs) and odorant-binding
proteins (OBPs), as their native sensing units to detect odours. Recent advances …

A review on natural sweeteners, sweet taste modulators and bitter masking compounds: structure-activity strategies for the discovery of novel taste molecules

JP An, Y Wang, SD Munger, X Tang - Critical Reviews in Food …, 2024 - Taylor & Francis
Growing demand for the tasty and healthy food has driven the development of low-calorie
sweeteners, sweet taste modulators, and bitter masking compounds originated from natural …

[HTML][HTML] Do gut microbes taste?

R Leung, M Covasa - Nutrients, 2021 - mdpi.com
Gut microbiota has emerged as a major metabolically active organ with critical functions in
both health and disease. The trillions of microorganisms hosted by the gastrointestinal tract …

[HTML][HTML] Beyond the flavour: the potential druggability of chemosensory G protein-coupled receptors

A Di Pizio, M Behrens, D Krautwurst - International journal of molecular …, 2019 - mdpi.com
G protein-coupled receptors (GPCRs) belong to the largest class of drug targets.
Approximately half of the members of the human GPCR superfamily are chemosensory …

COVID 19-induced smell and taste impairments: putative impact on physiology

N Meunier, L Briand, A Jacquin-Piques… - Frontiers in …, 2021 - frontiersin.org
Smell and taste impairments are recognized as common symptoms in COVID 19 patients
even in an asymptomatic phase. Indeed, depending on the country, in up to 85–90% of …

[HTML][HTML] Perfume and flavor engineering: A chemical engineering perspective

AE Rodrigues, I Nogueira, RPV Faria - Molecules, 2021 - mdpi.com
In the last two decades, scientific methodologies for the prediction of the design,
performance and classification of fragrance mixtures have been developed at the Laboratory …