Metformin is one of the most widely prescribed hypoglycemic drugs and has the potential to
treat many diseases. More and more evidence shows that metformin can regulate the …

Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …

The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …

Type 2 diabetes mellitus (T2DM) is a worldwide major health burden and heart failure (HF)
is the most common cardiovascular (CV) complication in affected patients. Therefore …

Diabetes mellitus, with a growing risk of develo** complications, has a significant negative
impact on cardiovascular health, including microvascular and macrovascular issues. This …

Cardiovascular mortality is a major cause of death among in type 2 diabetes (T2DM).
Endothelial dysfunction (ED) is a well-known important risk factor for the development of …

Optimal management of low-density lipoprotein cholesterol (LDL-C) is a central tenet in the
primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD) …

Background Insulin shares a limited physiological concentration range with other endocrine
hormones. Not only too low, but also too high systemic insulin levels are detrimental for body …

The design and synthesis of multifunctional chitosan hydrogels based on polymerized ionic
liquid and a near‐infrared (NIR) fluorescent probe (PIL‐CS) is a promising strategy, which …

Metformin, a well‐known AMPK agonist, has been widely used as the first‐line drug for
treating type 2 diabetes. There had been a significant concern regarding the use of …