Exosomes are 30–150 nm sized vesicles released by a variety of cells, and are found in
most physiological compartments (feces, blood, urine, saliva, breast milk). They can contain …

The intestinal tract consists of various types of cells, such as epithelial cells, Paneth cells,
macrophages, and lymphocytes, which constitute the intestinal immune system and play a …

Background & aims Tumor-infiltrating neutrophils (polymorphonuclear neutrophils [PMNs])
are a prominent feature of colorectal cancer (CRC), where they can promote cytotoxicity or …

Introduction: Neutrophils or polymorphonuclear cells (PMNs) account for a considerable
portion of the tumor immune stroma. Emerging single-cell transcriptomic analyses have …

Ulcerative colitis (UC) is one chronically remittent and progressive inflammatory disorder.
Chemokine receptor CXCR2 is reported to be involved in the pathogenesis of several …

Background Colitis‐associated cancer (CAC) is one of the most severe complications of
inflammatory bowel disease (IBD), which has caused a worse survival rate in IBD patients …

Background: Extracellular vesicles (EVs) mediate inflammation, immune responses, gut
barrier integrity, and intestinal homeostasis. Recently, the application of EVs in the treatment …

Inflammatory bowel disease is a heterogeneous intestinal inflammatory disorder, including
ulcerative colitis (UC) and Crohn's disease (CD). Existing studies have shown that the …

Abstract Interleukin (IL)-37 belongs to the IL-1 cytokine family. It has anti-inflammatory effects
on numerous autoimmune diseases such as asthma, psoriasis, inflammatory bowel disease …

The chapter explores the complicated relationship between immune cells and cancer drug
resistance. The immune cell composition in the tumor microenvironment (TME) …