The role of small molecules in musculoskeletal regeneration
KWH Lo, KM Ashe, HM Kan… - Regenerative medicine, 2012 - Taylor & Francis
The uses of bone morphogenetic proteins and parathyroid hormone therapeutics are fraught
with several fundamental problems, such as cost, protein stability, immunogenicity …
with several fundamental problems, such as cost, protein stability, immunogenicity …
Adult mesenchymal stem cells: is there a role for purine receptors in their osteogenic differentiation?
M Carluccio, S Ziberi, M Zuccarini, P Giuliani… - Purinergic …, 2020 - Springer
The role played by mesenchymal stem cells (MSCs) in contributing to adult tissue
homeostasis and damage repair thanks to their differentiation capabilities has raised a great …
homeostasis and damage repair thanks to their differentiation capabilities has raised a great …
Electromagnetic fields as first messenger in biological signaling: application to calmodulin-dependent signaling in tissue repair
A Pilla, R Fitzsimmons, D Muehsam, J Wu… - … et Biophysica Acta (BBA …, 2011 - Elsevier
BACKGROUND: The transduction mechanism for non-thermal electromagnetic field (EMF)
bioeffects has not been fully elucidated. This study proposes that an EMF can act as a first …
bioeffects has not been fully elucidated. This study proposes that an EMF can act as a first …
Low-power laser irradiation promotes the proliferation and osteogenic differentiation of human periodontal ligament cells via cyclic adenosine monophosphate
JY Wu, CH Chen, LY Yeh, ML Yeh, CC Ting… - International Journal of …, 2013 - nature.com
Retaining or improving periodontal ligament (PDL) function is crucial for restoring
periodontal defects. The aim of this study was to evaluate the physiological effects of low …
periodontal defects. The aim of this study was to evaluate the physiological effects of low …
A standardized extract of Coleus forskohlii root protects rats from ovariectomy-induced loss of bone mass and strength, and impaired bone material by osteogenic and …
Introduction In obese humans, Coleus forskohlii root extract (CF) protects against weight
gain owing to the presence of forskolin, an adenylate cyclase (AC) activator. As AC …
gain owing to the presence of forskolin, an adenylate cyclase (AC) activator. As AC …
[HTML][HTML] Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling
I D'Alimonte, E Nargi, A Lannutti, M Marchisio… - Stem cell …, 2013 - Elsevier
In this study, mesenchymal stem cells deriving from dental pulp (DPSCs) of normal human
impacted third molars, previously characterized for their ability to differentiate into …
impacted third molars, previously characterized for their ability to differentiate into …
The PDE4 Inhibitors Roflumilast and Rolipram Rescue ADO2 Osteoclast Resorption Dysfunction
JM Hong, RL Gerard-O'Riley, D Acton, I Alam… - Calcified Tissue …, 2024 - Springer
Abstract Autosomal Dominant Osteopetrosis type II (ADO2) is a rare bone disease of
impaired osteoclastic bone resorption caused by heterozygous missense mutations in the …
impaired osteoclastic bone resorption caused by heterozygous missense mutations in the …
[HTML][HTML] Activation of PKA/CREB signaling is involved in BMP9-induced osteogenic differentiation of mesenchymal stem cells
H Zhang, L Li, Q Dong, Y Wang, Q Feng, X Ou… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: BMP9 is highly capable of promoting osteogenic differentiation of
mesenchymal stem cells (MSCs) although the molecular mechanism involved is largely …
mesenchymal stem cells (MSCs) although the molecular mechanism involved is largely …
Map** calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors
Although calcium phosphate-containing biomaterials are promising scaffolds for bone
regenerative strategies, the osteoinductive capacity of such materials is poorly understood …
regenerative strategies, the osteoinductive capacity of such materials is poorly understood …
Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone
KM Tsang, MF Starost, M Nesterova… - Proceedings of the …, 2010 - National Acad Sciences
A population of stromal cells that retains osteogenic capacity in adult bone (adult bone
stromal cells or aBSCs) exists and is under intense investigation. Mice heterozygous for a …
stromal cells or aBSCs) exists and is under intense investigation. Mice heterozygous for a …