Otoacoustic emissions (OAEs) are sounds of cochlear origin, which can be recorded by a
microphone fitted into the ear canal. They are caused by the motion of the cochlea's sensory …

GABA is the main inhibitory neurotransmitter of the CNS. It is well established that activation
of GABAA receptors favors sleep. Three generations of hypnotics are based on these …

Background The authors investigated whether the sedative, or hypnotic, action of the
general anesthetic dexmedetomidine (a selective alpha-adrenoceptor agonist) activates …

The rostral hypothalamus and adjacent basal forebrain participate in the generation of
sleep, but the neuronal circuitry involved in this process remains poorly characterized …

The tuberomammillary nucleus (TMN) is the major source of histaminergic innervation of the
mammalian brain and is thought to play a major role in regulating wake–sleep states. We …

Primary headache syndromes, such as cluster headache and migraine, are widely
described as vascular headaches, although considerable clinical evidence suggests that …

We investigated the role of regionally discrete GABA (γ-aminobutyric acid) receptors in the
sedative response to pharmacological agents that act on GABAA receptors (muscimol …

Numerous lesion, stimulation and recording studies in experimental animals demonstrate
the importance of neurons within the preoptic/anterior hypothalamic area (POA) in the …

Sleep and body temperature are tightly interconnected in mammals: warming up our body
helps to fall asleep and the body temperature in turn drops while falling asleep. The preoptic …

Sleep and waking differ significantly in terms of behavior, metabolism, and neuronal activity.
Recent evidence indicates that sleep and waking also differ with respect to the expression of …