Advances in oral drug delivery systems: Challenges and opportunities

J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023 - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

[HTML][HTML] Surface design of nanocarriers: Key to more efficient oral drug delivery systems

H Spleis, M Sandmeier, V Claus… - Advances in colloid and …, 2023 - Elsevier
As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Advances in colon-targeted nano-drug delivery systems: challenges and solutions

M Naeem, UA Awan, F Subhan, J Cao… - Archives of pharmacal …, 2020 - Springer
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …

Nanoparticle-based oral drug delivery systems targeting the colon for treatment of ulcerative colitis

M Zhang, D Merlin - Inflammatory bowel diseases, 2018 - academic.oup.com
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): the story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

[HTML][HTML] Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant …

V Tinnirello, MG Zizzo, A Conigliaro, M Tabone… - Biomedicine & …, 2024 - Elsevier
Plant-derived nanovesicles (PDNVs) have recently emerged as natural delivery systems of
biofunctional compounds toward mammalian cells. Considering their already described …

[HTML][HTML] Research progress of natural product-based nanomaterials for the treatment of inflammation-related diseases

F Cao, SY Gui, X Gao, W Zhang, ZY Fu, LM Tao… - Materials & Design, 2022 - Elsevier
Inflammatory diseases present with dysregulated inflammatory reactions and oxidative
stress, resulting in heavy health-associated economic burden to society. Current mainstream …

[HTML][HTML] Natural product-based nanomedicine in treatment of inflammatory bowel disease

T Khare, SS Palakurthi, BM Shah, S Palakurthi… - International journal of …, 2020 - mdpi.com
Many synthetic drugs and monoclonal antibodies are currently in use to treat Inflammatory
Bowel Disease (IBD). However, they all are implicated in causing severe side effects and …

Genipin-crosslinked human serum albumin coating using a tannic acid layer for enhanced oral administration of curcumin in the treatment of ulcerative colitis

R Luo, M Lin, C Zhang, J Shi, S Zhang, Q Chen, Y Hu… - Food Chemistry, 2020 - Elsevier
Curcumin (CUR) is a promising edible phytochemical compound with ideal ulcerative colitis
(UC) treatment activity; however, it is characteristically instable in the digestive tract and has …

Stimulus-responsive drug delivery nanoplatforms for inflammatory bowel disease therapy

J Long, X Liang, Z Ao, X Tang, C Li, K Yan, X Yu… - Acta Biomaterialia, 2024 - Elsevier
Inflammatory bowel disease (IBD) manifests as inflammation in the colon, rectum, and ileum,
presenting a global health concern with increasing prevalence. Therefore, effective anti …