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Advances in oral drug delivery systems: Challenges and opportunities
J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023 - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …
oral drug delivery system faces the harsh physiological and physicochemical environment of …
[HTML][HTML] Surface design of nanocarriers: Key to more efficient oral drug delivery systems
H Spleis, M Sandmeier, V Claus… - Advances in colloid and …, 2023 - Elsevier
As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …
Advances in colon-targeted nano-drug delivery systems: challenges and solutions
Nano-drug delivery systems (NDDS) for colon-targeted drug delivery are an active area of
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
research on local diseases affecting the colon, such as ulcerative colitis, Crohn's disease …
Nanoparticle-based oral drug delivery systems targeting the colon for treatment of ulcerative colitis
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …
Curcumin and its modified formulations on inflammatory bowel disease (IBD): the story so far and future outlook
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …
[HTML][HTML] Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant …
Plant-derived nanovesicles (PDNVs) have recently emerged as natural delivery systems of
biofunctional compounds toward mammalian cells. Considering their already described …
biofunctional compounds toward mammalian cells. Considering their already described …
[HTML][HTML] Research progress of natural product-based nanomaterials for the treatment of inflammation-related diseases
Inflammatory diseases present with dysregulated inflammatory reactions and oxidative
stress, resulting in heavy health-associated economic burden to society. Current mainstream …
stress, resulting in heavy health-associated economic burden to society. Current mainstream …
[HTML][HTML] Natural product-based nanomedicine in treatment of inflammatory bowel disease
Many synthetic drugs and monoclonal antibodies are currently in use to treat Inflammatory
Bowel Disease (IBD). However, they all are implicated in causing severe side effects and …
Bowel Disease (IBD). However, they all are implicated in causing severe side effects and …
Genipin-crosslinked human serum albumin coating using a tannic acid layer for enhanced oral administration of curcumin in the treatment of ulcerative colitis
R Luo, M Lin, C Zhang, J Shi, S Zhang, Q Chen, Y Hu… - Food Chemistry, 2020 - Elsevier
Curcumin (CUR) is a promising edible phytochemical compound with ideal ulcerative colitis
(UC) treatment activity; however, it is characteristically instable in the digestive tract and has …
(UC) treatment activity; however, it is characteristically instable in the digestive tract and has …
Stimulus-responsive drug delivery nanoplatforms for inflammatory bowel disease therapy
J Long, X Liang, Z Ao, X Tang, C Li, K Yan, X Yu… - Acta Biomaterialia, 2024 - Elsevier
Inflammatory bowel disease (IBD) manifests as inflammation in the colon, rectum, and ileum,
presenting a global health concern with increasing prevalence. Therefore, effective anti …
presenting a global health concern with increasing prevalence. Therefore, effective anti …