Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity

GM Pagnotti, M Styner, G Uzer, VS Patel… - Nature Reviews …, 2019 - nature.com
Osteoporosis, a condition of skeletal decline that undermines quality of life, is treated with
pharmacological interventions that are associated with poor adherence and adverse effects …

Decellularized matrices for tissue engineering

T Hoshiba, H Lu, N Kawazoe… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Biomimetic scaffolds and substrates of extracellular matrices (ECMs)
play an important role in the regulation of cell function and in the guidance of new tissue …

Possible mechanisms for the effects of sound vibration on human health

L Bartel, A Mosabbir - Healthcare, 2021 - mdpi.com
This paper presents a narrative review of research literature to “map the landscape” of the
mechanisms of the effect of sound vibration on humans including the physiological …

[HTML][HTML] Mesenchymal stem cell responses to mechanical stimuli

RM Delaine-Smith, GC Reilly - Muscles, ligaments and tendons …, 2012 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have the potential to replace or restore the function of
damaged tissues and offer much promise in the successful application of tissue engineering …

In Vitro Three-Dimensional Bone Tissue Models: From Cells to Controlled and Dynamic Environment

G Bouët, D Marchat, M Cruel, L Malaval… - Tissue Engineering Part …, 2015 - liebertpub.com
Most of our knowledge of bone cell physiology is derived from experiments carried out in
vitro on polystyrene substrates. However, these traditional monolayer cell cultures do not …

The effects of locomotion on bone marrow mesenchymal stem cell fate: insight into mechanical regulation and bone formation

Y Sun, Y Yuan, W Wu, L Lei, L Zhang - Cell & bioscience, 2021 - Springer
Bone marrow mesenchymal stem cells (BMSCs) refer to a heterogeneous population of cells
with the capacity for self-renewal. BMSCs have multi-directional differentiation potential and …

Yoda1 enhanced low-magnitude high-frequency vibration on osteocytes in regulation of MDA-MB-231 breast cancer cell migration

CY Lin, X Song, Y Ke, A Raha, Y Wu, M Wasi, L Wang… - Cancers, 2022 - mdpi.com
Simple Summary Bone metastasis is a severe complication that contributes significantly to
the morbidity and mortality of breast cancer patients. Although mechanical loading was …

The effects of vibration loading on adipose stem cell number, viability and differentiation towards bone-forming cells

L Tirkkonen, H Halonen, J Hyttinen… - Journal of the …, 2011 - royalsocietypublishing.org
Mechanical stimulation is an essential factor affecting the metabolism of bone cells and their
precursors. We hypothesized that vibration loading would stimulate differentiation of human …

[PDF][PDF] The effect of whole body vibration on fracture healing-a systematic review

J Wang, KS Leung, SK Chow, WH Cheung - Eur Cell Mater, 2017 - ecmjournal.org
This systematic review examines the efficacy and safety of whole body vibration (WBV) on
fracture healing. A systematic literature search was conducted with relevant keywords in …

[PDF][PDF] Osteogenic differentiation of bone marrow-derived mesenchymal stromal cells on bone-derived scaffolds: effect of microvibration and role of ERK1/2 activation

Y Zhou, X Guan, Z Zhu, S Gao, C Zhang, C Li… - Eur Cell …, 2011 - ecmjournal.org
Although in vivo studies have shown that low-magnitude, high-frequency (LMHF) vibration
(LM:< 1× g; HF: 20-90 Hz) exhibits anabolic effects on skeletal homeostasis, the underlying …