Nanomedical approaches in the realm of rheumatoid arthritis

AF Radu, SG Bungau - Ageing research reviews, 2023 - Elsevier
Rheumatoid arthritis (RA) is a heterogeneous autoimmune inflammatory disorder defined by
the damage to the bone and cartilage in the synovium, which causes joint impairment and …

Harnessing nanomedicine for cartilage repair: design considerations and recent advances in biomaterials

H Zhou, Z Zhang, Y Mu, H Yao, Y Zhang, DA Wang - ACS nano, 2024 - ACS Publications
Cartilage injuries are escalating worldwide, particularly in aging society. Given its limited self-
healing ability, the repair and regeneration of damaged articular cartilage remain formidable …

Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials

Y Zhu, T Zhao, M Liu, S Wang, S Liu, Y Yang, Y Yang… - Nano Today, 2022 - Elsevier
Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …

[HTML][HTML] Biological drug and drug delivery-mediated immunotherapy

Q **ao, X Li, Y Li, Z Wu, C Xu, Z Chen, W He - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

The therapeutic landscape of rheumatoid arthritis: current state and future directions

S Shams, JM Martinez, JRD Dawson, J Flores… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical,
emotional and socioeconomic consequences. Despite advances in targeted biologic and …

Nanoparticle–cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy

X Li, B Dai, J Guo, L Zheng, Q Guo, J Peng, J Xu… - Nano-micro letters, 2021 - Springer
Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …

Effects of engineered nanoparticles on the innate immune system

Y Liu, J Hardie, X Zhang, VM Rotello - Seminars in immunology, 2017 - Elsevier
Engineered nanoparticles (NPs) have broad applications in industry and nanomedicine.
When NPs enter the body, interactions with the immune system are unavoidable. The innate …

[HTML][HTML] Nanomedicines for the treatment of rheumatoid arthritis: State of art and potential therapeutic strategies

Q Wang, X Qin, J Fang, X Sun - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Increasing understanding of the pathogenesis of rheumatoid arthritis (RA) has remarkably
promoted the development of effective therapeutic regimens of RA. Nevertheless, the …

Recent advances in nanoparticle-based drug delivery systems for rheumatoid arthritis treatment

S Nasra, D Bhatia, A Kumar - Nanoscale advances, 2022 - pubs.rsc.org
Nanotechnology has increasingly emerged as a promising tool for exploring new
approaches, from treating complex conditions to early detection of the onset of multiple …

Toxicological behavior of gold nanoparticles on various models: influence of physicochemical properties and other factors

OB Adewale, H Davids… - International journal of …, 2019 - journals.sagepub.com
Potential applications of gold nanoparticles in biomedicine have increasingly been reported
on account of the ease of synthesis, bioinert characteristics, optical properties, chemical …