Green Tea (Camellia sinensis): A Review of Its Phytochemistry, Pharmacology, and Toxicology

T Zhao, C Li, S Wang, X Song - Molecules, 2022 - mdpi.com
Objectives Green tea (Camellia sinensis) is a kind of unfermented tea that retains the natural
substance in fresh leaves to a great extent. It is regarded as the second most popular drink …

Flavonoids in cancer and apoptosis

M Abotaleb, SM Samuel, E Varghese, S Varghese… - Cancers, 2018 - mdpi.com
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …

Natural polyphenols for prevention and treatment of cancer

Y Zhou, J Zheng, Y Li, DP Xu, S Li, YM Chen, HB Li - Nutrients, 2016 - mdpi.com
There is much epidemiological evidence that a diet rich in fruits and vegetables could lower
the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols …

Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Polyphenols as antitumor agents targeting key players in cancer-driving signaling pathways

MH Cháirez-Ramírez, KG de la Cruz-López… - Frontiers in …, 2021 - frontiersin.org
Polyphenols constitute an important group of natural products that are traditionally
associated with a wide range of bioactivities. These are usually found in low concentrations …

Interaction of dietary polyphenols and gut microbiota: Microbial metabolism of polyphenols, influence on the gut microbiota, and implications on host health

G Catalkaya, K Venema, L Lucini, G Rocchetti… - Food …, 2020 - Wiley Online Library
The human gastrointestinal tract is inhabited by a vast number of microorganisms that are
called as the microbiota. Each individual harbors a unique gut microbial composition, this …

EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction

J Zhao, A Blayney, X Liu, L Gandy, W **, L Yan… - Nature …, 2021 - nature.com
Epigallocatechin gallate (EGCG) from green tea can induce apoptosis in cancerous cells,
but the underlying molecular mechanisms remain poorly understood. Using SPR and NMR …

[HTML][HTML] A review on anti-cancer effect of green tea catechins

Z Cheng, Z Zhang, Y Han, J Wang, Y Wang… - Journal of functional …, 2020 - Elsevier
This article reviewed inhibitory activities of green tea catechins (GTCs) against various
tumorigenesis and their suppressive effects on cancer cell progression, metastasis, and …

Current evidence on the effect of dietary polyphenols intake on chronic diseases

C Costa, A Tsatsakis, C Mamoulakis, M Teodoro… - Food and Chemical …, 2017 - Elsevier
Polyphenols are secondary metabolites of plants. They comprise several antioxidant
compounds and they are generally considered to be involved in the defense against human …

Molecular mechanisms underlying health benefits of tea compounds

A Shang, J Li, DD Zhou, RY Gan, HB Li - Free Radical Biology and …, 2021 - Elsevier
Tea is one of the three most widely consumed beverages in the world, not only because of
its unique flavor but also due to its various health benefits. The bioactive components in tea …