Current strategies for exosome cargo loading and targeting delivery

H Zeng, S Guo, X Ren, Z Wu, S Liu, X Yao - Cells, 2023 - mdpi.com
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …

Biogenesis, isolation, and detection of exosomes and their potential in therapeutics and Diagnostics

S Sonbhadra, Mehak, LM Pandey - Biosensors, 2023 - mdpi.com
The increasing research and rapid developments in the field of exosomes provide insights
into their role and significance in human health. Exosomes derived from various sources …

Recent advances in nanomaterials for neural applications: opportunities and challenges

N Sisubalan, R Shalini, S Ramya, BS Sivamaruthi… - …, 2023 - Taylor & Francis
Nanomedicines are promising for delivering drugs to the central nervous system, though
their precision is still being improved. Fortifying nanoparticles with vital molecules can …

The role of exosomes in the diagnosis of Parkinson's disease

Q Shi, W Kang, Z Liu, X Zhu - Heliyon, 2023 - cell.com
Parkinson's disease is a common neurodegenerative disease characterized by intracellular
aggregation of misfolded α-synuclein as a major pathological hallmark. Exosomes are cell …

[HTML][HTML] Delivering therapeutic RNA into the brain using extracellular vesicles

P Shirmast, MA Shahri, A Brent, A Idris… - … Therapy Nucleic Acids, 2024 - cell.com
RNA science has experienced a surge, particularly its application to vaccine and therapeutic
development. Delivery of RNA molecules into the brain remains one of the biggest …

Effective removal of textile dye via synergy of adsorption and photocatalysis over ZnS nanoparticles: Synthesis, modeling, and mechanism

S Ouni, F Yahia, NBH Mohamed, M Bouzidi… - Heliyon, 2024 - cell.com
In this work, we prepared sulfur-zinc nanoparticles (ZnS-TGA) functionalized with
thioglycolic acid by a hydrothermal method and tested their photodegradation ability by solar …

The major hypotheses of Alzheimer's disease: related nanotechnology-based approaches for its diagnosis and treatment

C Cáceres, B Heusser, A Garnham, E Moczko - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is a well-known chronic neurodegenerative disorder that leads to
the progressive death of brain cells, resulting in memory loss and the loss of other critical …

Engineered Extracellular Vesicles: A potential treatment for regeneration

W Cheng, C Xu, Y Su, Y Shen, Q Yang, Y Zhao, Y Zhao… - Iscience, 2023 - cell.com
Extracellular vesicles (EVs) play a critical role in various physiological and pathological
processes. EVs have gained recognition in regenerative medicine due to their …

Proteomics provides insights into the theranostic potential of extracellular vesicles

M Abyadeh, M Alikhani, M Mirzaei, V Gupta… - Advances in Protein …, 2024 - Elsevier
Extracellular vesicles (EVs) encompass a diverse range of membranous structures derived
from cells, including exosomes and microvesicles. These vesicles are present in biological …

Subty** and prognostic model construction based on vesicle-mediated transport-related genes in colorectal cancer

W Wu, T Huang, S Li, G Gong, D Zhao… - Human Molecular …, 2024 - academic.oup.com
Background Colorectal cancer (CRC) is impacted by various environmental and genetic
variables. Dysregulation of vesicle-mediated transport-related genes (VMTRGs) has been …