Recent advancements in single-cell RNA sequencing (scRNA-seq) technology have
enabled the comprehensive profiling of gene expression patterns at the single-cell level …

Cell− cell communication, as a basic feature of multicellular organisms, is crucial for
maintaining the biological functions and microenvironmental homeostasis of cells, organs …

Background Metabolite-associated cell communications play critical roles in maintaining
human biological function. However, most existing tools and resources focus only on ligand …

Understanding intricate gene regulatory networks (GRNs) orchestrating responses to abiotic
stresses is crucial for enhancing climate resilience in crop plants. Recent advancements in …

The scientific community has long benefited from the opportunities provided by data reuse.
Recognizing the need to identify the challenges and bottlenecks to reuse in the agricultural …

Single-cell multimodal sequencing parallelly captures multiple modalities of the same cell,
providing unparalleled insights into cell heterogeneity and cell dynamics. For example, joint …

Abstract The 2023 Nucleic Acids Research Database Issue contains 178 papers ranging
across biology and related fields. There are 90 papers reporting on new databases and 82 …

Advances in sequencing and imaging technologies offer a unique opportunity to unravel cell
heterogeneity and develop new immunotherapy strategies for cancer research. There is an …

Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung
disease. Multiple research has revealed that the extracellular matrix (ECM) may be …

To uncover the role of satellite cells (SCs) in paravertebral muscle development and aging,
we constructed a single-nucleus transcriptomic atlas of mouse paravertebral muscle across …