Myeloid cells are the most abundant immune components of the tumour microenvironment,
where they have a variety of functions, ranging from immunosuppressive to …

Macrophages represent a key component of the tumor microenvironment (TME) and are
largely associated with poor prognosis. Therapeutic targeting of macrophages has …

Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer in adults.
When ccRCC is localized to the kidney, surgical resection or ablation of the tumor is often …

The extracellular matrix (ECM) is a vital component of the tumor microenvironment, which
interplays with stromal and tumor cells to stimulate the capacity of cancer cells to proliferate …

Defining the ontogeny of tumor-associated macrophages (TAM) is important to develop
therapeutic targets for mesothelioma. We identified two distinct macrophage populations in …

Cancer continues to be a substantial health concern and a leading cause of death in the
United States and around the world. Therefore, it is important to continue to explore the …

Over the past few decades, with the rise of immunotherapies, tumor infiltrating immune cells
were increasingly investigated. Indeed, they may represent biomarkers for patient outcome …

Bone tumors, including primary bone tumors and bone metastases, have been plagued by
poor prognosis for decades. Although most tumor tissue is removed, clinicians are still …

During the last decade, non-invasive methods such as liquid biopsy have slowly replaced
traditional imaging and invasive pathological methods used to diagnose and monitor …

Abstract Background Solute Carrier Family 31 Member 1 (SLC31A1) has recently been
identified as a cuproptosis-regulatory gene. Recent studies have indicated that SLC31A1 …