In vivo NIR-II fluorescence imaging for biology and medicine

F Wang, Y Zhong, O Bruns, Y Liang, H Dai - Nature Photonics, 2024 - nature.com
Owing to reduced light scattering and tissue autofluorescence, in vivo fluorescence imaging
in the 1,000–3,000-nm near-infrared II (NIR-II) spectral range can afford non-invasive …

Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

NIR-II light in clinical oncology: opportunities and challenges

Z Zhang, Y Du, X Shi, K Wang, Q Qu, Q Liang… - Nature Reviews …, 2024 - nature.com
Novel strategies utilizing light in the second near-infrared region (NIR-II; 900–1,880 nm
wavelengths) offer the potential to visualize and treat solid tumours with enhanced precision …

Brightness of fluorescent organic nanomaterials

AH Ashoka, IO Aparin, A Reisch… - Chemical Society …, 2023 - pubs.rsc.org
Brightness is a fundamental property of fluorescent nanomaterials reflecting their capacity to
absorb and emit light. In sensing materials, brightness is crucial for high-sensitivity (bio) …

Versatile types of inorganic/organic NIR-IIa/IIb fluorophores: from strategic design toward molecular imaging and theranostics

Y Liu, Y Li, S Koo, Y Sun, Y Liu, X Liu, Y Pan… - Chemical …, 2021 - ACS Publications
In vivo imaging in the second near-infrared window (NIR-II, 1000–1700 nm), which enables
us to look deeply into living subjects, is producing marvelous opportunities for biomedical …

Multifunctional AIE nanosphere-based “nanobomb” for trimodal imaging-guided photothermal/photodynamic/pharmacological therapy of drug-resistant bacterial …

B Li, W Wang, L Zhao, D Yan, X Li, Q Gao, J Zheng… - ACS …, 2023 - ACS Publications
Injudicious or inappropriate use of antibiotics has led to the prevalence of drug-resistant
bacteria, posing a huge menace to global health. Here, a self-assembled aggregation …

The chemistry of organic contrast agents in the NIR‐II window

J Mu, M **ao, Y Shi, X Geng, H Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Optical imaging, especially fluorescence and photoacoustic imaging, is a non‐invasive
imaging approach with high spatial and temporal resolution and high sensitivity, compared …

Molecularly engineered room-temperature phosphorescence for biomedical application: from the visible toward second near-infrared window

B Chang, J Chen, J Bao, T Sun, Z Cheng - Chemical Reviews, 2023 - ACS Publications
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Molecular engineering of NIR‐II fluorophores for improved biomedical detection

Z Lei, F Zhang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …