Keratin expression in human tissues and neoplasms

PG Chu, LM Weiss - Histopathology, 2002 - Wiley Online Library
Keratin expression in human tissues and neoplasms Keratin filaments constitute type I and
type II intermediate filaments (IFs), with at least 20 subtypes named keratin 1–20. Since …

Keratins and the skin

E Fuchs - Annual review of cell and developmental biology, 1995 - annualreviews.org
Keratins are the major structural proteins of the vertebrate epidermis and its appendages,
constituting up to 85% of a fully differentiated keratinocyte. Together with actin …

cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.

DZ Fisher, N Chaudhary… - Proceedings of the …, 1986 - National Acad Sciences
The amino acid sequences deduced from cDNA clones of human lamin A and lamin C show
identity between these two lamins except for an extra 9.0-kDa carboxyl-terminal tail that is …

Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23. 1

MJ Neville, EC Johnstone, RT Walton - Human mutation, 2004 - Wiley Online Library
The dopamine D2 receptor has been extensively studied in relation to alcoholism,
substance abuse, and nicotine dependence. The most frequently examined polymorphism …

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

FD McKeon, MW Kirschner, D Caput - Nature, 1986 - nature.com
Abstract The A, B and C lamins are the major proteins of the nuclear envelope. The
complete nucleotide sequence of the coding region of the A and C lamins shows that these …

Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium

KU Hong, SD Reynolds, S Watkins, E Fuchs… - The American journal of …, 2004 - Elsevier
Commitment of the pulmonary epithelium to bronchial and bronchiolar airway lineages
occurs during the transition from pseudoglandular to cannalicular phases of lung …

Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses

PA Coulombe, ME Hutton, A Letal, A Hebert, AS Paller… - Cell, 1991 - cell.com
Previously we demonstrated that transgenic mice expressing mutant basal epidermal keratin
genes exhibited a phenotype resembling a group of autosomal dominant human skin …

Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm

S Kim, PA Coulombe - Genes & development, 2007 - genesdev.cshlp.org
Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are
encoded by a large family of differentially expressed genes. Owing in part to their properties …

Antibody markers of basal cells in complex epithelia

PE Purkis, JB Steel, IC Mackenzie… - Journal of cell …, 1990 - journals.biologists.com
In the course of immunohistochemical studies it has become apparent that there is a distinct
phenotype of keratin expression that is shared by basal epithelial cells in a variety of …

Structure, function, and differentiation of the keratinocyte

RL Eckert - Physiological reviews, 1989 - journals.physiology.org
The skin is the largest organ system of the body. It consists of an epithelial layer (epidermis),
a connective tissue layer (dermis), and an adipose layer (hypodermis). Its overall function is …