Formation of UV-induced DNA damage contributing to skin cancer development

J Cadet, T Douki - Photochemical & Photobiological Sciences, 2018‏ - pubs.rsc.org
UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …

Nucleic acids as a playground for the computational study of the photophysics and photochemistry of multichromophore assemblies

L Martínez Fernández, F Santoro… - Accounts of Chemical …, 2022‏ - ACS Publications
Conspectus The interaction between light and multichromophoric assemblies (MCAs) is the
primary event of many fundamental processes, from photosynthesis to organic photovoltaics …

Plasmon-mediated photoelectrochemical hot-hole oxidation coupling reactions of adenine on nanostructured silver electrodes

YQ Su, J Liu, R Huang, HT Yang, MX Li… - The Journal of …, 2023‏ - ACS Publications
Surface-enhanced Raman spectroscopy (SERS) has been widely applied in the
identification and characterization of DNA structures with high efficiency. Especially, the …

Multiple electronic and structural factors control cyclobutane pyrimidine dimer and 6–4 thymine–thymine photodimerization in a DNA duplex

I Conti, L Martínez‐Fernández… - … A European Journal, 2017‏ - Wiley Online Library
The T–T photodimerization paths leading to the formation of cyclobutane pyrimidine dimer
(CPD) and 6–4 pyrimidine pyrimidone (64‐PP), the two main DNA photolesions, have been …

Adenine radicals generated in alternating AT duplexes by direct absorption of low-energy UV radiation

A Banyasz, T Ketola, L Martínez-Fernández… - Faraday …, 2018‏ - pubs.rsc.org
There is increasing evidence that the direct absorption of photons with energies that are
lower than the ionization potential of nucleobases may result in oxidative damage to DNA …

UV-induced adenine radicals induced in DNA A-tracts: spectral and dynamical characterization

A Banyasz, TM Ketola, A Muñoz-Losa… - The journal of …, 2016‏ - ACS Publications
Adenyl radicals generated in DNA single and double strands,(dA) 20 and (dA) 20·(dT) 20, by
one-and two-photon ionization by 266 nm laser pulses decay at 600 nm with half-times of …

Exciton trap** dynamics in DNA multimers

R Borrego-Varillas, G Cerullo… - The Journal of Physical …, 2019‏ - ACS Publications
Using as a model the single adenine strand (dA) 20, we study the ultrafast evolution of
electronic excitations in DNA with a time resolution of 30 fs. Our transient absorption spectra …

[HTML][HTML] Populations and dynamics of guanine radicals in DNA strands—Direct versus indirect generation

E Balanikas, A Banyasz, G Baldacchino, D Markovitsi - Molecules, 2019‏ - mdpi.com
Guanine radicals, known to be involved in the damage of the genetic code and aging, are
studied by nanosecond transient absorption spectroscopy. They are generated in single …

Vibrational assignments of cyclic dimers and inter-monomers of adenine relating FT-IR, FT-Raman and UV spectra with SQMFF and DFT calculations

PG Cataldo, MA Iramain, MV Castillo… - … Acta Part A: Molecular …, 2024‏ - Elsevier
In this work, three different cyclic dimers and a tetramer of adenine taken from the
experimental structure determined by X-ray diffraction have been studied by combination of …

Photoactivated proton coupled electron transfer in DNA: insights from quantum mechanical calculations

L Martinez-Fernandez, R Improta - Faraday Discussions, 2018‏ - pubs.rsc.org
The energetics of the two main proton coupled electron transfer processes that could occur
in DNA are determined by means of time dependent-DFT calculations, using the M052X …