[HTML][HTML] Roles of extracellular HSPs as biomarkers in immune surveillance and immune evasion

EA Taha, K Ono, T Eguchi - International journal of molecular sciences, 2019 - mdpi.com
Extracellular heat shock proteins (ex-HSPs) have been found in exosomes, oncosomes,
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …

Theileria's Strategies and Effector Mechanisms for Host Cell Transformation: From Invasion to Immortalization

K Woods, C Perry, F Brühlmann, P Olias - Frontiers in cell and …, 2021 - frontiersin.org
One of the first events that follows invasion of leukocytes by Theileria sporozoites is the
destruction of the surrounding host cell membrane and the rapid association of the …

Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans

S Chatterjee, U Tatu - PLoS neglected tropical diseases, 2017 - journals.plos.org
Background Thermotolerance is an essential attribute for pathogenesis of Cryptococcus as
exemplified by the fact that only two species in the genus, which can grow at 37° C, are …

Susceptibility to disease (tropical theileriosis) is associated with differential expression of host genes that possess motifs recognised by a pathogen DNA binding …

SD Larcombe, P Capewell, K Jensen, W Weir… - PloS one, 2022 - journals.plos.org
Background Knowledge of factors that influence the outcome of infection are crucial for
determining the risk of severe disease and requires the characterisation of pathogen-host …

Theileria secretes proteins to subvert its host leukocyte

S Tajeri, G Langsley - Biology of the Cell, 2021 - Wiley Online Library
Theileria parasites are classified in the phylum Apicomplexa that includes several genera of
medical and veterinary importance such as Plasmodium, Babesia, Toxoplasma and …

[HTML][HTML] 17-DMAG inhibits the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice

A Guswanto, AB Nugraha, B Tuvshintulga… - International Journal for …, 2018 - Elsevier
Abstract Heat shock protein 90 (Hsp90) is a chaperone protein that stabilizes cells during
stress or non-stress responses. Previous reports have shown that Hsp90 is a potential drug …

Nucleotide binding domain and leucine-rich repeat pyrin domain-containing protein 12: characterization of its binding to hematopoietic cell kinase

Y Zhang, CT Okamoto - International Journal of Biological …, 2020 - pmc.ncbi.nlm.nih.gov
Protein-protein interactions are key to define the function of nucleotide binding domain
(NBD) and leucine-rich repeat (LRR) family, pyrin domain (PYD)-containing protein 12 …

Anti-piroplasmic activity of novobiocin as heat shock protein 90 inhibitor against in vitro cultured Theileria equi and Babesia caballi parasites

A Suthar, C Maji, A Gopalkrishnan, SH Raval… - Ticks and Tick-borne …, 2021 - Elsevier
Theileria equi and Babesia caballi are the causative agents of equine piroplasmosis (EP).
Currently, imidocarb dipropionate (ID) is the only available drug for treating the clinical form …

[PDF][PDF] IJP: Drugs and Drug Resistance

A Guswantoa, AB Nugrahaa, B Tuvshintulgaa… - academia.edu
ABSTRACT Heat shock protein 90 (Hsp90) is a chaperone protein that stabilizes cells
during stress or non-stress responses. Previous reports have shown that Hsp90 is a …

[PDF][PDF] Studies on the development of diagnostic methods and chemotherapeutics of babesiosis

A Guswanto - 2017 - obihiro.repo.nii.ac.jp
Babesſaparasiteshave beenfound formorethana Centuryand causeasignificantburdenin
thelivestockindustryandemerging diseaseinhumans. Thedistribution ofthediseaseremainsas …