A preponderance of evidence obtained from genetically modified mice and human
population studies reveals the association of apolipoprotein E (apoE) deficiency and …

Introduction. Diabetes mellitus as the most prevalent metabolic disease is a multifactorial
disease which is influenced by environmental and genetic factors. In this systematic review …

Background Lipoprotein-related mechanisms have been associated with damage to the
cardiovascular system in diabetic patients. Apolipoprotein E gene which affects the …

Apolipoprotein (apo) E4 is a major genetic risk factor for a wide spectrum of inflammatory
metabolic diseases, including atherosclerosis, diabetes, and Alzheimer disease. This study …

Background and aim Diabetes raises the risk of dementia, mortality, and cognitive decline in
the elderly, potentially because of hereditary variables such as APOE. In this study, we aim …

Type 2 diabetes mellitus (T2DM) is a highly complicated metabolic disorder for which there
is worldwide effort for the identification of susceptibility genes. Polymorphisms of the …

Background Apolipoprotein E (APOE) gene mediates lipoprotein clearance and is one of the
most studied candidate genes for type 2 diabetes mellitus (T2DM) and coronary artery …

Background Numerous reports investigated the involvement of apolipoprotein E (APOE)
polymorphisms with elevated risk of type 2 diabetes mellitus (T2DM) and obesity. The …

The apolipoprotein apoE plays a key role in cholesterol and lipid metabolism. There are
three isoforms of this protein, one of which, apoE4, is the major risk factor for Alzheimer's …

A non-optimal plasma concentration of lipids is among the major modifiable risk factors of
atherosclerosis. Therefore, the prevention of cardiovascular disease by means of lipid …