[HTML][HTML] Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls
Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …
Targeting cardiac stem cell senescence to treat cardiac aging and disease
E Cianflone, M Torella, F Biamonte, A De Angelis… - Cells, 2020 - mdpi.com
Adult stem/progenitor are a small population of cells that reside in tissue-specific niches and
possess the potential to differentiate in all cell types of the organ in which they operate. Adult …
possess the potential to differentiate in all cell types of the organ in which they operate. Adult …
Pharmacological clearance of senescent cells improves cardiac remodeling and function after myocardial infarction in female aged mice
Cardiovascular diseases (CVD) are predominantly an aging disease. Important sex-specific
differences exist and the mechanism (s) by which this sex-by-age interaction influences CVD …
differences exist and the mechanism (s) by which this sex-by-age interaction influences CVD …
From spheroids to organoids: the next generation of model systems of human cardiac regeneration in a dish
Organoids are tiny, self-organized, three-dimensional tissue cultures that are derived from
the differentiation of stem cells. The growing interest in the use of organoids arises from their …
the differentiation of stem cells. The growing interest in the use of organoids arises from their …
Revealing the crucial roles of suppressive immune microenvironment in cardiac myxoma progression
Z Jiang, Q Kang, H Qian, Z Xu, H Tong… - … and Targeted Therapy, 2024 - nature.com
Cardiac myxoma is a commonly encountered tumor within the heart that has the potential to
be life-threatening. However, the cellular composition of this condition is still not well …
be life-threatening. However, the cellular composition of this condition is still not well …
[HTML][HTML] Atrial fibrillation: epigenetic aspects and role of sodium-glucose cotransporter 2 inhibitors
M Donniacuo, A De Angelis, M Telesca… - Pharmacological …, 2023 - Elsevier
Atrial fibrillation (AF) is the most frequent arrhythmia and is associated with substantial
morbidity and mortality. Pathophysiological aspects consist in the activation of pro-fibrotic …
morbidity and mortality. Pathophysiological aspects consist in the activation of pro-fibrotic …
Myocardial regeneration protocols towards the routine clinical scenario: An unseemly path from bench to bedside
Heart failure secondary to cardiomyocyte loss and/or dysfunction is the number one killer
worldwide. The field of myocardial regeneration with its far-reaching primary goal of cardiac …
worldwide. The field of myocardial regeneration with its far-reaching primary goal of cardiac …
The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system
GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that causes coronavirus disease 2019 (COVID-19) has led to 47 m infected cases and 1. 2 m …
that causes coronavirus disease 2019 (COVID-19) has led to 47 m infected cases and 1. 2 m …
Combined lymphocyte/monocyte count, D-dimer and iron status predict COVID-19 course and outcome in a long-term care facility
Abstract Background The Sars-CoV-2 can cause severe pneumonia with multiorgan
disease; thus, the identification of clinical and laboratory predictors of the progression …
disease; thus, the identification of clinical and laboratory predictors of the progression …
Imaging of cardiac masses: an updated overview
VM Parato, S Nocco, G Alunni, F Becherini… - Journal of …, 2022 - journals.lww.com
Studying cardiac masses is one of the most challenging tasks for cardiac imagers. The aim
of this review article is to focus on the modern imaging of cardiac masses proceeding …
of this review article is to focus on the modern imaging of cardiac masses proceeding …