In modern laboratory diagnostics of cardiovascular diseases (CVD), there is a clear
tendency toward an increase in the sensitivity of methods for determining key CVD …

Management of patients presenting to the Emergency Department with chest pain is
continuously evolving. In the setting of acute coronary syndrome, the availability of high …

All known direct and indirect approaches for the estimation of reference intervals (RIs) have
difficulties in processing very skewed data with a high percentage of values at or below the …

Simple Summary Cardiovascular diseases, including myocardial infarction, are among the
most common diseases worldwide. Markers associated with the diagnosis of myocardial …

The study of the metabolism of endogenous molecules is not only of great fundamental
significance but also of high practical importance, since many molecules serve as drug …

Aims High-sensitivity cardiac troponin (hs-cTn) assays are used for detection of myocardial
infarction (MI). Ninety-ninth percentiles show wide inter-assay variation. The use of sex …

Background High sensitivity cardiac troponin-T (hs-TnT) has been associated with mortality
in patients hospitalized with COVID-19. We aimed to determine if hs-TnT levels and their …

The diagnosis of acute myocardial injury requires a rise and/or fall of cardiac troponin (cTn)
on serial testing, with at least one concentration above the 99th percentile value of a normal …

Background This study aims to investigate the impact of age and sex on high-sensitivity
cardiac troponin T (hs-cTnT) and establish 99th percentile upper reference limits (URLs) in …

Background Chronic kidney disease (CKD) are associated with acute myocardial infarction
(AMI). High-sensitive cardiac troponin (hs-cTn) has been evidenced to enhance the early …