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Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …
more than 500 million population worldwide. OA was believed to be caused by the wearing …
Risk of metabolic abnormalities in osteoarthritis: a new perspective to understand its pathological mechanisms
Although aging has traditionally been viewed as the most important risk factor for
osteoarthritis (OA), an increasing amount of epidemiological evidence has highlighted the …
osteoarthritis (OA), an increasing amount of epidemiological evidence has highlighted the …
A DNA tetrahedron-based ferroptosis-suppressing nanoparticle: superior delivery of curcumin and alleviation of diabetic osteoporosis
Y Li, Z Cai, W Ma, L Bai, E Luo, Y Lin - Bone Research, 2024 - nature.com
Diabetic osteoporosis (DOP) is a significant complication that poses continuous threat to the
bone health of patients with diabetes; however, currently, there are no effective treatment …
bone health of patients with diabetes; however, currently, there are no effective treatment …
Iron homeostasis and ferroptosis in human diseases: mechanisms and therapeutic prospects
Iron, an essential mineral in the body, is involved in numerous physiological processes,
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway
Z Gong, Y Wang, L Li, X Li, B Qiu, Y Hu - Food and Chemical Toxicology, 2023 - Elsevier
Osteoarthritis (OA) is a common degenerative joint disease, mainly presented by the
deterioration of articular cartilage. Amounts of data demonstrated this deterioration is …
deterioration of articular cartilage. Amounts of data demonstrated this deterioration is …
Undenatured type II collagen and its role in improving osteoarthritis
R Xu, J Wu, L Zheng, M Zhao - Ageing research reviews, 2023 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease, affecting 32.5 million US adults or 242
million people worldwide. There is no cure for OA. Many animal and clinical trials showed …
million people worldwide. There is no cure for OA. Many animal and clinical trials showed …
[HTML][HTML] Supramolecular self-assembly of EGCG-selenomethionine nanodrug for treating osteoarthritis
H Yu, Z Song, J Yu, B Ren, Y Dong, Y You, Z Zhang… - Bioactive materials, 2024 - Elsevier
Osteoarthritis (OA) has emerged as a significant health concern among the elderly
population, with increasing attention paid to ferroptosis-induced OA in recent years …
population, with increasing attention paid to ferroptosis-induced OA in recent years …
MicroRNA-targeting nanomedicines for the treatment of intervertebral disc degeneration
Low back pain stands as a pervasive global health concern, afflicting almost 80% of adults
at some point in their lives with nearly 40% attributable to intervertebral disc degeneration …
at some point in their lives with nearly 40% attributable to intervertebral disc degeneration …
Hypoxia and matrix metalloproteinase 13‐responsive hydrogel microspheres alleviate osteoarthritis progression in vivo
T Zhou, H **ong, SY Yao, S Wang, S Li, J Chang… - Small, 2024 - Wiley Online Library
The occurrence of osteoarthritis (OA) is highly associated with the inflammatory hypoxic
microenvironment. Yet currently no attention has been paid to fabricating hypoxia …
microenvironment. Yet currently no attention has been paid to fabricating hypoxia …
Hydrogels for ameliorating osteoarthritis: mechanical modulation, anti‐inflammation, and regeneration
Osteoarthritis (OA) is a chronic and degenerative disease with limited clinical options for
effective suppression. Recently, significant endeavors have been explored to reveal its …
effective suppression. Recently, significant endeavors have been explored to reveal its …