Western societies notice an increasing interest in plant-based eating patterns such as
vegetarian and vegan, yet potential effects on the body and brain are a matter of debate …

Cerebral small vessel disease (CSVD) is a generic term used for intracranial vascular
disorders caused by the structural changes of cerebral microvessels, including the small …

Context Chronic obesity is associated with several complications, including cognitive
impairment and dementia. However, we have only piecemeal knowledge of the mechanisms …

International Journal of Epidemiology, 2023, e66–e79 https://doi. org/10.1093/ije/dyac114
Advance Access Publication Date: 28 May 2022 Cohort Profile comprehensive molecular …

The spinal cord is part of the central nervous system (CNS) and serves to connect the brain
to the peripheral nervous system and peripheral tissues. The cell types that primarily …

Abstract Purpose of Review Obesity is one of the most serious public health concerns.
Excess adipose tissue, particularly with a centralized distribution, is associated with …

Recent and accumulating work in experimental animal models and humans shows that diet
has a much more pervasive and prominent role than previously thought in modulating …

Associations between brain and obesity are bidirectional: changes in brain structure and
function underpin over-eating, while chronic adiposity leads to brain atrophy. Investigating …

Obesity is a global pandemic associated with macro-and microvascular endothelial
dysfunction. Microvascular endothelial dysfunction has recently emerged as a significant risk …

Background Sarcopenic obesity, a clinical and functional condition characterized by the
coexistence of obesity and sarcopenia, has not been investigated in relation to dementia risk …