Chronic cough is globally prevalent across all age groups. This disorder is challenging to
treat because many pulmonary and extrapulmonary conditions can present with chronic …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

In 2011, a European Respiratory Society Task Force embarked on a process to determine
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …

Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …

Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive
myelinated sensory nerves play essential roles in regulating cough. These vagal sensory …

Transient receptor potential (TRP) channels are a superfamily of non-selective cation
channels that act as polymodal sensors in many tissues throughout mammalian organisms …

Cough is a reflex action of the respiratory tract that is used to clear the upper airways.
Chronic cough lasting for more than 8 weeks is common in the community. The causes …

BACKGROUND Cough is the most common symptom for which individuals seek medical
advice 1, 2. An acute cough is often the most prominent symptom of the common cold, which …

1.1 Background Patients with cough frequently present to clinicians working in both primary
and secondary care. 1, 2 Acute cough, which often follows an upper respiratory tract …

Chronic cough is a common symptom that can be a daunting challenge for clinicians since
treatment of the underlying cause does not always provide adequate relief, an obvious …