As drug carriers for cancer treatment, stimulus-responsive polymer nanomaterials are a
major research focus. These nanocarriers respond to specific stimulus signals (eg, pH …

The general principles of interaction between bor (on) ic acids and sugars in aqueous media
are discussed with a focus on the structural aspects that play a role with respect to the …

Artificial stimuli-responsive surfaces that can mimic the dynamic function of living systems
have attracted much attention. However, there exist few artificial systems capable of …

Ligand-mediated targeting of nanocarriers to tumors is an attractive strategy for increasing
the efficiency of chemotherapies. Sialylated glycans represent a propitious target as they are …

CRISPR/dCas9 systems can precisely control endogenous gene expression without
interrupting host genomic sequence and have provided a novel and feasible strategy for the …

The expression of cell surface glycans terminating with sialic acid (SA) residues has been
found to correlate with various disease states there among cancer. We here report a novel …

Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids
readily form boronate esters with the 1, 2-and 1, 3-diols of saccharides, such as those that …

We present a cationic polymer architecture composed of phenylboronic acid (PBA), sugar-
installed polyethylenimine (PEI), and polyethylene glycol (PEG). The chemical bonding of …

Ferroptosis is a non-apoptotic cell death pathway characterized by the accumulation of lipid-
peroxy radicals within the affected cells. Here, we investigate the synergistic capacity of …

Alternations of sialic acid (SA) content on cell surface glycan chains have been implicated in
numerous normal and pathological processes including developments, differentiations, and …