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Placental model as an important tool to study maternal-fetal interface
The placenta is a temporary organ that plays critical roles at the maternal-fetal interface.
Normal development and function of the placenta is dependent on hormonal signaling …
Normal development and function of the placenta is dependent on hormonal signaling …
Bioengineering approaches for placental research
Research into the human placenta's complex functioning is complicated by a lack of suitable
physiological in vivo models. Two complementary approaches have emerged recently to …
physiological in vivo models. Two complementary approaches have emerged recently to …
Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood
Characterization of blood flow rheology in hematological disorders is critical for
understanding disease pathophysiology. Existing methods to measure blood rheological …
understanding disease pathophysiology. Existing methods to measure blood rheological …
A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta
Multi-scale structural assessment of biological soft tissue is challenging but essential to gain
insight into structure–function relationships of tissue/organ. Using the human placenta as an …
insight into structure–function relationships of tissue/organ. Using the human placenta as an …
Anomalous diffusion of deformable particles in a honeycomb network
Transport of deformable particles in a honeycomb network is studied numerically. It is shown
that the particle deformability has a strong impact on their distribution in the network. For …
that the particle deformability has a strong impact on their distribution in the network. For …
Structure-function relationships in the feto-placental circulation from in silico interpretation of micro-CT vascular structures
A well-functioning placenta is critical for healthy fetal development, as the placenta brings
fetal blood in close contact with nutrient rich maternal blood, enabling exchange of nutrients …
fetal blood in close contact with nutrient rich maternal blood, enabling exchange of nutrients …
[HTML][HTML] Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability
Since the full development of the ex vivo dual perfusion model of the human placenta
cotyledon, the technique has provided essential insight into how nutrients, lipids, gases …
cotyledon, the technique has provided essential insight into how nutrients, lipids, gases …
Multiscale three-dimensional imaging of the placenta
Placental function involves multiple different processes which operate at different scales
from centimetres to nanometres. Everything that the placenta does from mediating blood …
from centimetres to nanometres. Everything that the placenta does from mediating blood …
Computational modeling of the interactions between the maternal and fetal circulations in human pregnancy
In pregnancy, fetal growth is supported by its placenta. In turn, the placenta is nourished by
maternal blood, delivered from the uterus, in which the vasculature is dramatically …
maternal blood, delivered from the uterus, in which the vasculature is dramatically …
[HTML][HTML] The role of the 3Rs for understanding and modeling the human placenta
Modeling the physiology of the human placenta is still a challenge, despite the great number
of scientific advancements made in the field. Animal models cannot fully replicate the …
of scientific advancements made in the field. Animal models cannot fully replicate the …