Corticobasal syndrome (CBS) is a clinical syndrome characterised by progressive
asymmetric limb rigidity and apraxia with dystonia, myoclonus, cortical sensory loss and …

Tauopathies are both clinical and pathological heterogeneous disorders characterized by
neuronal and/or glial accumulation of misfolded tau protein. It is now well understood that …

Recent mechanistic and structural studies have challenged the classical tauopathy
classification approach and revealed the complexity and heterogeneity of tau pathology in …

The advent of PET ligands that bind tau pathology has enabled the quantification and
visualization of tau pathology in aging and in Alzheimer disease (AD). There is strong …

Positron emission tomography (PET) imaging of tau aggregation in Alzheimer's disease
(AD) is hel** to map and quantify the in vivo progression of AD pathology. To date, no …

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The detection and staging of Alzheimer's disease (AD) using non-invasive imaging
biomarkers is of substantial clinical importance. Positron emission tomography (PET) …

Background Several magnetic resonance imaging (MRI) measures have been suggested as
progression biomarkers in progressive supranuclear palsy (PSP), and some PSP staging …

Previous studies have developed and explored magnetic resonance imaging (MRI)-based
machine learning models for predicting Alzheimer's disease (AD). However, limited research …

Background We recently developed a positron emission tomography (PET) probe,[18F] PM‐
PBB3, to detect tau lesions in diverse tauopathies, including mixed three‐repeat and four …