Management of hemorrhagic shock: physiology approach, timing and strategies

FG Bonanno - Journal of clinical medicine, 2022 - mdpi.com
Hemorrhagic shock (HS) management is based on a timely, rapid, definitive source control
of bleeding/s and on blood loss replacement. Stop** the hemorrhage from progressing …

Bench-to-bedside review: vasopressin in the management of septic shock

JA Russell - Critical Care, 2011 - Springer
This review of vasopressin in septic shock differs from previous reviews by providing more
information on the physiology and pathophysiology of vasopressin and vasopressin …

How we escalate vasopressor and corticosteroid therapy in patients with septic shock

B Teja, NA Bosch, AJ Walkey - Chest, 2023 - Elsevier
Septic shock is defined by the need for vasopressor agents to correct hypotension and lactic
acidosis resulting from infection, with 30%-40% case fatality rates. The care of patients with …

Incidence of hypotension according to the discontinuation order of vasopressors in the management of septic shock: a prospective randomized trial (DOVSS)

K Jeon, JU Song, CR Chung, JH Yang, GY Suh - Critical Care, 2018 - Springer
Background Vasopressin (AVP) is commonly added to norepinephrine (NE) to reverse
shock in patients with sepsis. However, there are no data to support the appropriate strategy …

Hemorrhagic shock: the “physiology approach”

FG Bonanno - Journal of emergencies, trauma, and shock, 2012 - journals.lww.com
A shift of approach from 'clinics trying to fit physiology'to the one of 'physiology to clinics', with
interpretation of the clinical phenomena from their physiological bases to the tip of the …

Discontinuation of vasopressin before norepinephrine in the recovery phase of septic shock

DA Hammond, K McCain, JT Painter… - Journal of intensive …, 2019 - journals.sagepub.com
Background: Guidance for the discontinuation of vasopressors in the recovery phase of
septic shock is limited. Norepinephrine is more easily titrated; however, septic shock is a …

Evaluating vasopressor discontinuation strategies in patients with septic shock on concomitant norepinephrine and vasopressin infusions

N Musallam, D Altshuler, C Merchan… - Annals of …, 2018 - journals.sagepub.com
Background: There is little data guiding clinicians on how to discontinue vasopressors
among septic shock patients on concomitant norepinephrine (NE) and vasopressin (VP) …

Hemodynamic instability secondary to vasopressin withdrawal in septic shock

BD Bissell, C Magee, P Moran… - Journal of intensive …, 2019 - journals.sagepub.com
Rationale: Vasopressors such as norepinephrine are first line for support of mean arterial
pressure (MAP) in the management of septic shock. Their use, however, is commonly …

Effects of norepinephrine and vasopressin discontinuation order in the recovery phase of septic shock: a systematic review and individual patient data meta‐analysis

DA Hammond, GL Sacha, BD Bissell… - … : The Journal of …, 2019 - Wiley Online Library
Objective The impact of vasopressin and norepinephrine discontinuation order in the
recovery phase of septic shock remains controversial. This systematic review and patient …

Hypotension risk based on vasoactive agent discontinuation order in patients in the recovery phase of septic shock

GL Sacha, SW Lam, A Duggal, H Torbic… - … : The Journal of …, 2018 - Wiley Online Library
Study Objectives Patients with septic shock often require vasoactive agents for
hemodynamic support; however, the optimal approach to discontinuing these agents once …