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Exploring the frontiers of neuroimaging: a review of recent advances in understanding brain functioning and disorders
C Yen, CL Lin, MC Chiang - Life, 2023 - mdpi.com
Neuroimaging has revolutionized our understanding of brain function and has become an
essential tool for researchers studying neurological disorders. Functional magnetic …
essential tool for researchers studying neurological disorders. Functional magnetic …
From imbalance to impairment: the central role of reactive oxygen species in oxidative stress-induced disorders and therapeutic exploration
S Afzal, AS Abdul Manap, A Attiq… - Frontiers in …, 2023 - frontiersin.org
Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …
health issues, including metabolic problems, cancers, and neurological conditions. Our …
Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology
TM Goralski, L Meyerdirk, L Breton, L Brasseur… - Nature …, 2024 - nature.com
A key hallmark of Parkinson's disease (PD) is Lewy pathology. Composed of α-synuclein,
Lewy pathology is found both in dopaminergic neurons that modulate motor function, and …
Lewy pathology is found both in dopaminergic neurons that modulate motor function, and …
Recent advances on the molecular mechanisms of exercise-induced improvements of cognitive dysfunction
Y Lu, FQ Bu, F Wang, L Liu, S Zhang, G Wang… - Translational …, 2023 - Springer
Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …
Gut microbiota, circulating cytokines and dementia: a Mendelian randomization study
D Ji, WZ Chen, L Zhang, ZH Zhang, LJ Chen - Journal of …, 2024 - Springer
Background Some studies have shown that gut microbiota may be associated with
dementia. However, the causal effects between gut microbiota and different types of …
dementia. However, the causal effects between gut microbiota and different types of …
Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-κB/NLRP3 pathway
J Wu, Y Han, H Xu, H Sun, R Wang, H Ren… - Science advances, 2023 - science.org
Neuroinflammation is a pathological change that is involved in the progression of
Parkinson's disease. Dysfunction of chaperone-mediated autophagy (CMA) has …
Parkinson's disease. Dysfunction of chaperone-mediated autophagy (CMA) has …
Functional brain networks in the evaluation of patients with neurodegenerative disorders
M Perovnik, T Rus, KA Schindlbeck… - Nature Reviews …, 2023 - nature.com
Network analytical tools are increasingly being applied to brain imaging maps of resting
metabolic activity (PET) or blood oxygenation-dependent signals (functional MRI) to …
metabolic activity (PET) or blood oxygenation-dependent signals (functional MRI) to …
Preventing Parkinson's disease: an environmental agenda
BR De Miranda, SM Goldman… - Journal of …, 2022 - journals.sagepub.com
Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …
Dementia prevention and treatment: a narrative review
Importance Dementia affects 10% of those 65 years or older and 35% of those 90 years or
older, often with profound cognitive, behavioral, and functional consequences. As the baby …
older, often with profound cognitive, behavioral, and functional consequences. As the baby …
[HTML][HTML] The role of glymphatic system in Alzheimer's and Parkinson's disease pathogenesis
FR Buccellato, M D'Anca, M Serpente, A Arighi… - Biomedicines, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common cause of neurodegenerative dementia, whilst
Parkinson's disease (PD) is a neurodegenerative movement disorder. These two …
Parkinson's disease (PD) is a neurodegenerative movement disorder. These two …