Liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based proteomics is a
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …

Introduction Investigating the taxonomic and functional composition of human microbiomes
can aid in the understanding of disease etiologies, diagnosis, and therapy monitoring for …

Measuring the expression levels of membrane proteins (MPs) is crucial for understanding
cell differentiation and tissue specificity, defining disease characteristics, identifying …

The application of fecal metaproteomics to large-scale studies of the gut microbiota requires
high-throughput analysis and standardized experimental protocols. Although high …

The standard bottom‐up proteomic workflow is comprised of sample preparation, data
acquisition, and data analysis. While the latter two parts have made considerable advances …

The analysis of biological samples is highly valuable for disease diagnosis and treatment,
forensic examination, and public safety. However, the serious matrix interference effect …

There is a high unmet need for early detection approaches for diffuse gastric cancer (DGC).
We examined whether the stool proteome of mouse models of gastric cancer (GC) and …

Next-generation shotgun proteomics is one of the most valuable tools for gaining insight into
the function of organisms. By providing a list of peptides and abundance information …

Bacteria are widely present in nature, such as water, soil, atmosphere, food, human and
animal body surfaces, and lumens connected to nature, and are closely related to human …

Gastric cancer (GC) is the 4 th deadliest cancer worldwide in 2020 according to the WHO.
Poor patient prognosis is attributed to late-stage diagnosis and lack of effective treatments …