As a result of the adaptation of life to an aerobic environment, nature has evolved a panoply
of metalloproteins for oxidative metabolism and protection against reactive oxygen species …

Utilization of O2 as an abundant and environmentally benign oxidant is of great interest in
the design of bioinspired synthetic catalytic oxidation systems. Metalloenzymes activate O2 …

Naturally produced halogenated compounds are ubiquitous across all domains of life where
they perform a multitude of biological functions and adopt a diversity of chemical structures …

Metal-exchanged zeolites are a class of heterogeneous catalysts that perform important
functions ranging from selective hydrocarbon oxidation to remediation of NO x pollutants …

High selectivity and exquisite control over the outcome of reactions entice chemists to use
biocatalysts in organic synthesis. However, many useful reactions are not accessible …

Mononuclear non-heme Fe (II)-and 2-oxoglutarate (2OG)-dependent oxygenases comprise
a large family of enzymes that utilize an Fe (IV)-oxo intermediate to initiate diverse oxidative …

Selective functionalization of unactivated C–H bonds, water oxidation, and dioxygen
reduction are extremely important reactions in the context of finding energy carriers and …

Since our initial report in 1976, the oxygen rebound mechanism has become the consensus
mechanistic feature for an expanding variety of enzymatic C–H functionalization reactions …

The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

The rational design of well-defined, first-row transition metal complexes that can activate
dioxygen has been a challenging goal for the synthetic inorganic chemist. The activation of …