Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance

C Liao, X Huang, Q Wang, D Yao, W Lu - Frontiers in cellular and …, 2022 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …

Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review

FF Tuon, LR Dantas, PH Suss, VS Tasca Ribeiro - Pathogens, 2022 - mdpi.com
Pseudomonas aeruginosa is associated with several human infections, mainly related to
healthcare services. In the hospital, it is associated with resistance to several antibiotics …

Flavonols and flavones as potential anti‐inflammatory, antioxidant, and antibacterial compounds

MSS Chagas, MD Behrens… - Oxidative medicine …, 2022 - Wiley Online Library
Plant preparations have been used to treat various diseases and discussed for centuries.
Research has advanced to discover and identify the plant components with beneficial effects …

Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy

S Hossain, Z Urbi, H Karuniawati, RB Mohiuddin… - Life, 2021 - mdpi.com
Infectious disease (ID) is one of the top-most serious threats to human health globally,
further aggravated by antimicrobial resistance and lack of novel immunization options …

Progress in and promise of bacterial quorum sensing research

M Whiteley, SP Diggle, EP Greenberg - Nature, 2017 - nature.com
This Review highlights how we can build upon the relatively new and rapidly develo**
field of research into bacterial quorum sensing (QS). We now have a depth of knowledge …

Quorum-sensing regulation of antimicrobial resistance in bacteria

X Zhao, Z Yu, T Ding - Microorganisms, 2020 - mdpi.com
Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome
and is related to cell density. The high-density colony population can generate a sufficient …

Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action

R Roy, M Tiwari, G Donelli, V Tiwari - Virulence, 2018 - Taylor & Francis
Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …

Microbiologically influenced corrosion and current mitigation strategies: a state of the art review

R Jia, T Unsal, D Xu, Y Lekbach, T Gu - International biodeterioration & …, 2019 - Elsevier
In nature, microbes tend to form synergistic biofilms on a wide range of materials using
extracellular polymeric substances to embed sessile cells. Problematic biofilms provide …

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

SW Dickey, GYC Cheung, M Otto - Nature Reviews Drug Discovery, 2017 - nature.com
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

Quorum-sensing systems as targets for antivirulence therapy

T Defoirdt - Trends in microbiology, 2018 - cell.com
The development of novel therapies to control diseases caused by antibiotic-resistant
pathogens is one of the major challenges we are currently facing. Many important plant …