Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

2. Methods This is a narrative review based on the authors' research and on that of groups
working in the same area. Given the vast amount of data in the field, it is not possible to …

Exosomes denote a class of secreted nanoparticles defined by size, surface protein and
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …

Glioblastoma is the most aggressive malignant tumor of the central nervous system with a
low survival rate. The difficulty of obtaining this tumor material represents a major limitation …

Background Hypoxia is a critical aspect of the glioma microenvironment and has been
associated with poor prognosis and resistance to various therapies. However, the …

Background Patients with glioblastoma (GBM) have a dramatically poor prognosis. The
recent REGOMA trial suggested an overall survival (OS) benefit of regorafenib in recurrent …

Glioblastoma stem cells (GSCs) are cells with a self-renewal ability and capacity to initiate
tumors upon serial transplantation that have been linked to tumor cell heterogeneity. Most …

Glioblastoma (GBM) is a highly lethal cancer that is universally refractory to the standard
multimodal therapies of surgical resection, radiation, and chemotherapy treatment …

Simple Summary Exosomes symbolize membrane-enclosed entities of endocytic origin.
They play an important role in the intracellular communication by shuttling proteins, nucleic …

Glioblastoma is the most aggressive form of brain tumor originating from glial cells with a
maximum life expectancy of 14.6 months. Despite the establishment of multiple promising …