Intervertebral disc degeneration is a major cause of low back pain. Despite its long history
and large socio-economical impact in western societies, the initiation and progress of disc …

Many experimental testing techniques have been adopted in order to provide an
understanding of the biomechanics of the human intervertebral disc (IVD). The aim of this …

The cartilaginous endplates (CEP) are key components of the intervertebral disc (IVD)
necessary for sustaining the nutrition of the disc while distributing mechanical loads and …

Bioinks play a central role in 3D-bioprinting by providing the supporting environment within
which encapsulated cells can endure the stresses encountered during the digitally driven …

BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …

Aligned electrospun scaffolds are promising tools for engineering fibrous musculoskeletal
tissues, as they reproduce the mechanical anisotropy of these tissues and can direct …

Since the publication of the 2nd edition of White and Panjabi׳ s textbook, Clinical
Biomechanics of the Spine in 1990, there has been considerable research on the …

BACKGROUND: Major deficits of many finite element models of the lumbar spine are the
oversimplification, assumed constellation of the material properties or the insufficiently …

Compared to a healthy intervertebral disc, the geometry and the material properties of the
involved tissues are altered in a degenerated disc. It is not completely understood how this …

The intervertebral disc has a composite structure consisting of a gelatinous proteoglycanrich
nucleus pulposus surrounded by a collagen-rich anulus fibrosus. The proteoglycan in the …