[HTML][HTML] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice

S Prasad, AK Tyagi… - Cancer research and …, 2014 - synapse.koreamed.org
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral …

Oral delivery of anticancer drugs: challenges and opportunities

K Thanki, RP Gangwal, AT Sangamwar… - Journal of controlled …, 2013 - Elsevier
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

Curcumin-loaded nanostructured lipid carriers (NLCs) for nasal administration: design, characterization, and in vivo study

RG Madane, HS Mahajan - Drug delivery, 2016 - Taylor & Francis
Cancer nanotherapeutics is beginning to overwhelm the global research and viewed to be
the revolutionary treatment regime in the medical field. This investigation describes the …

Systematic approach for the formulation and optimization of solid lipid nanoparticles of efavirenz by high pressure homogenization using design of experiments for …

S Gupta, R Kesarla, N Chotai, A Misra… - Biomed research …, 2017 - Wiley Online Library
The nonnucleoside reverse transcriptase inhibitors, used for the treatment of HIV infections,
are reported to have low bioavailability pertaining to high first‐pass metabolism, high protein …

Quality-by-design of nanopharmaceuticals–a state of the art

T Bastogne - Nanomedicine: Nanotechnology, Biology and Medicine, 2017 - Elsevier
Abstract Pharmaceutical Quality-by-Design is a risk-based approach of drug development
relying on the understanding of both the product and the process. This state of the art …

Nanonization of curcumin by antisolvent precipitation: process development, characterization, freeze drying and stability performance

D Yadav, N Kumar - International journal of pharmaceutics, 2014 - Elsevier
The present work aims to investigate applicability of antisolvent precipitation method for
preparation of nanosized curcumin and to control their characteristics by determining the …

Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectives

G Kumar, S Mittal, K Sak, HS Tuli - Life sciences, 2016 - Elsevier
In recent years, natural compounds have received considerable attention in preventing and
curing most dreadful diseases including cancer. The reason behind the use of natural …

Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human …

PY Chang, SF Peng, CY Lee… - International …, 2013 - spandidos-publications.com
Curcumin is a polyphenolic compound which possesses anticancer potential. It has been
shown to induce cell death in a variety of cancer cells, however, its effect on CAL27‑cisplatin …

Counteracting arsenic toxicity: curcumin to the rescue?

A Bahrami, T Sathyapalan, SA Moallem… - Journal of hazardous …, 2020 - Elsevier
Arsenicosis leads to various irreversible damages in several organs and is considered to be
a carcinogen. The effects of chronic arsenic poisoning are a result of an imbalance between …

QbD-based systematic development of novel optimized solid self-nanoemulsifying drug delivery systems (SNEDDS) of lovastatin with enhanced biopharmaceutical …

S Beg, PS Sandhu, RS Batra, RK Khurana, B Singh - Drug delivery, 2015 - Taylor & Francis
Of late, solid self-nanoemulsifying drug delivery systems (S-SNEDDS) have been
extensively sought-after owing to their superior portability, drug loading, stability and patient …