Persistence of chloroquine resistance alleles in malaria endemic countries: a systematic review of burden and risk factors

M Ocan, D Akena, S Nsobya, MR Kamya, R Senono… - Malaria journal, 2019 - Springer
Background Chloroquine, a previous highly efficacious, easy to use and affordable anti-
malarial agent was withdrawn from malaria endemic regions due to high levels of …

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification

SO Oyola, CV Ariani, WL Hamilton, M Kekre… - Malaria journal, 2016 - Springer
Background Translating genomic technologies into healthcare applications for the malaria
parasite Plasmodium falciparum has been limited by the technical and logistical difficulties …

High prevalence of Pfcrt 76T and Pfmdr1 N86 genotypes in malaria infected patients attending health facilities in East Shewa zone, Oromia Regional State, Ethiopia

J Hassen, GS Alemayehu, H Dinka, L Golassa - Malaria journal, 2022 - Springer
Background Plasmodium falciparum resistance to series of anti-malarial drugs is a major
challenge in efforts to control and/or eliminate malaria globally. In 1998, following the …

Antimalarial drug resistance profiling of Plasmodium falciparum infections in Ghana using molecular inversion probes and next-generation sequencing

BA Mensah, O Aydemir, JL Myers-Hansen… - Antimicrobial agents …, 2020 - journals.asm.org
ABSTRACT A key drawback to monitoring the emergence and spread of antimalarial drug
resistance in sub-Saharan Africa is early detection and containment. Next-generation …

[HTML][HTML] Contrasting Asymptomatic and Drug Resistance Gene Prevalence of Plasmodium falciparum in Ghana: Implications on Seasonal Malaria Chemoprevention

CC Dieng, L Gonzalez, K Pestana, SB Dhikrullahi… - Genes, 2019 - mdpi.com
Malaria is a significant public health problem in Ghana. Seasonal Malaria Chemoprevention
(SMC) using a combination of sulfadoxine-pyrimethamine and amodiaquine has been …

In vivo efficacy of top five surveyed Ghanaian herbal anti-malarial products

D Wilmot, EO Ameyaw, D Amoako-Sakyi… - Malaria journal, 2017 - Springer
Background Anti-malarial herbal preparations (HPs) continue to enjoy high patronage in
Ghana despite reports that the artemisinin-based combination therapy (ACT), the …

Biennial surveillance of Plasmodium falciparum anti-malarial drug resistance markers in Democratic Republic of Congo, 2017 and 2019

DM Yobi, NK Kayiba, DM Mvumbi, R Boreux… - BMC Infectious …, 2022 - Springer
Background Because of the loss of chloroquine (CQ) effectiveness, the Democratic Republic
of Congo (DRC)'s malaria treatment policy replaced CQ by sulfadoxine–pyrimethamine (SP) …

Overdiagnosis and overtreatment of malaria in children in a secondary healthcare centre in Sekondi-Takoradi, Ghana

VN Orish, JY Ansong, OS Onyeabor… - Tropical …, 2016 - journals.sagepub.com
Overdiagnosis and overtreatment of malaria is a major problem in children in malaria-
endemic countries. This retrospective study identified children who were admitted with fever …

Effectiveness of Intermittent Preventive Treatment in Pregnancy with Sulphadoxine‐Pyrimethamine against Submicroscopic falciparum Malaria in Central Region …

EK Nwaefuna, R Afoakwah, VN Orish… - Journal of …, 2015 - Wiley Online Library
Malaria infections undetectable by microscopy but detectable by Polymerase Chain
Reaction (PCR)(submicroscopic malaria) are common in endemic areas like Ghana …

Characteristics of asymptomatic Plasmodium spp. parasitaemia in Kwahu-Mpraeso, a malaria endemic mountainous district in Ghana, West Africa

EDA Owusu, V Buabeng, S Dadzie, CA Brown… - Malaria journal, 2016 - Springer
Background Malaria control efforts in Ghana have reduced the countrywide average malaria
prevalence from 71% in 2000 to about 51% in 2012; however, its main focus is on …