Computational fluid dynamics modelling of human upper airway: A review
Background and objective Human upper airway (HUA) has been widely investigated by
many researchers covering various aspects, such as the effects of geometrical parameters …
many researchers covering various aspects, such as the effects of geometrical parameters …
Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract
Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …
tracts are critical to aerosol drug delivery and evaluation of inhalation products …
Revisiting airflow and aerosol transport phenomena in the deep lungs with microfluidics
J Sznitman - Chemical Reviews, 2021 - ACS Publications
The dynamics of respiratory airflows and the associated transport mechanisms of inhaled
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …
aerosols characteristic of the deep regions of the lungs are of broad interest in assessing …
Nanotherapeutics for pulmonary drug delivery: An emerging approach to overcome respiratory diseases
Pulmonary diseases pose an immense threat to global health. Several nanotherapeutics-
based approaches aimed to tackle pulmonary ailments in recent years. The current …
based approaches aimed to tackle pulmonary ailments in recent years. The current …
Towards whole-lung simulations of aerosol deposition: A model of the deep lung
In silico methods can be used to estimate regional deposition of inhaled aerosols in regions
of the lung that are inaccessible by direct measurements. Knowledge of deposited dose is …
of the lung that are inaccessible by direct measurements. Knowledge of deposited dose is …
Advanced human-relevant in vitro pulmonary platforms for respiratory therapeutics
A Artzy-Schnirman, SA Raviv, OD Flikshtain… - Advanced drug delivery …, 2021 - Elsevier
Over the past years, advanced in vitro pulmonary platforms have witnessed exciting
developments that are pushing beyond traditional preclinical cell culture methods. Here, we …
developments that are pushing beyond traditional preclinical cell culture methods. Here, we …
Tutorial: Understanding the transport, deposition, and translocation of particles in human respiratory systems using Computational Fluid-Particle Dynamics and …
Dynamic modeling of how particulate matter (PM) transport, deposit, and translocate from
human respiratory systems to systemic regions subject to indoor and outdoor exposures are …
human respiratory systems to systemic regions subject to indoor and outdoor exposures are …
Mucus, airway and plume temperature effects on pMDI-drug delivery in a mouth-throat airway: Experimental and numerical studies
Effective pulmonary drug delivery through pressurized-metered dose inhalers (pMDIs)
depends on accurately targeting pharmaceutical aerosols to specific lung areas. Achieving …
depends on accurately targeting pharmaceutical aerosols to specific lung areas. Achieving …
Glottis motion effects on the particle transport and deposition in a subject-specific mouth-to-trachea model: A CFPD study
Abstract Background Computational Fluid-Particle Dynamics (CFPD) models have been
employed to predict lung aerosol dynamics for decades, estimating the delivery efficiency of …
employed to predict lung aerosol dynamics for decades, estimating the delivery efficiency of …
In situ-Like Aerosol Inhalation Exposure for Cytotoxicity Assessment Using Airway-on-Chips Platforms
Lung exposure to inhaled particulate matter (PM) is known to injure the airway epithelium
via inflammation, a phenomenon linked to increased levels of global morbidity and mortality …
via inflammation, a phenomenon linked to increased levels of global morbidity and mortality …