A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …

The human gut microbiome is a critical component of digestion, breaking down complex
carbohydrates, proteins, and to a lesser extent fats that reach the lower gastrointestinal tract …

The inflammatory bowel diseases (IBDs), which include Crohn's disease (CD) and ulcerative
colitis (UC), are multifactorial chronic conditions of the gastrointestinal tract. While IBD has …

The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy
metabolism, glucose tolerance, immune system maturation and function in humans …

Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …

The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

Irritable bowel syndrome (IBS) is a functional disorder which affects a large proportion of the
population globally. The precise etiology of IBS is still unknown, although consensus …

Crohn's disease and ulcerative colitis are prototypical complex diseases characterized by
chronic and heterogeneous manifestations, induced by interacting environmental, genomic …

Mass spectrometry-and nuclear magnetic resonance-based metabolomic studies comparing
diseased versus healthy individuals have shown that microbial metabolites are often the …