Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is increasingly
affecting pediatric and adult populations. Neuropsychiatric manifestations (ie, cognitive …

Neuropsychiatric manifestations occur frequently and are challenging to diagnose in
childhood-onset systemic lupus erythematosus (SLE). Most patients with childhood-onset …

Background Epidemiologic studies have shown that Alzheimer's disease (AD) and related
dementias (ADRD) are seen more frequently with asthma, especially with greater asthma …

Cognitive dysfunction is one of the five psychiatric syndromes recognised by the American
College of Rheumatologists neuropsychiatric lupus nomenclature committee. Cognitive …

The diagnosis and pathology of neuropsychiatric systemic lupus erythematosus (NPSLE)
remains challenging. Herein, we used multimodal imaging to assess anatomical and …

Objective To evaluate a safe, noninvasive magnetic resonance imaging (MRI) method to
measure regional blood–brain barrier integrity and investigate its relationship with …

Cognitive dysfunction (CD) is a neurologic complication of pediatric systemic lupus
erythematosus (SLE) that remains poorly understood and understudied, despite the …

The diagnosis of Neuropsychiatric systemic lupus erythematosus disease (NPSLE) is
challenging. The Automated Neuropsychological Assessment Metrics (ANAM) has been …

Cognitive dysfunction is a common aspect of systemic lupus erythematosus (SLE) and is
increasingly reported as a problem by patients. In many cases the exact cause is unclear …

SLE can affect the nervous system, most frequently the brain, in up to 50% of patients and
the first step in assessment should be to ensure a robust diagnosis of SLE.