The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Detection of circulating tumor cells and epithelial progenitor cells: a comprehensive study

S Fuloria, V Subramaniyan, G Gupta… - Journal of …, 2023 - dl.begellhouse.com
Technological advancement to enhance tumor cells (TC) has allowed discovery of various
cellular bio-markers: cancer stem cells (CSC), circulating tumor cells (CTC), and endothelial …

[HTML][HTML] Neuroprotective effects of phytochemicals against aluminum chloride-induced Alzheimer's disease through ApoE4/LRP1, wnt3/β-catenin/gsk3β, and TLR4 …

AME Hamdan, FHJ Alharthi, AH Alanazi, SZ El-Emam… - Pharmaceuticals, 2022 - mdpi.com
Background: Alzheimer's disease (AD) is a neurodegenerative disorder that is associated
with abnormal cognition. AD is aided in its initiation and progression by hereditary and …

Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog

M Dai, X Gui, S Jia, S Lv, H Dou, W Cui - Acta Pharmacologica Sinica, 2023 - nature.com
Abstract Dl-3-n-butylphthalide (NBP) is a small-molecule drug used in the treatment of
ischemic stroke in China, which is proven to ameliorate the symptoms of ischemic stroke and …

Traditional Chinese medicines treat ischemic stroke and their main bioactive constituents and mechanisms

G Fan, M Liu, J Liu, Y Huang, W Mu - Phytotherapy Research, 2024 - Wiley Online Library
Ischemic stroke (IS) remains one of the leading causes of death and disability in humans.
Unfortunately, none of the treatments effectively provide functional benefits to patients with …

Implementing losartan potassium-laden pegylated nanocubic vesicles as a novel nanoplatform to alleviate cisplatin-induced nephrotoxicity via blocking apoptosis and …

HF Salem, MM Nafady, RA Khallaf, AR Abdel-Sattar… - Life Sciences, 2024 - Elsevier
Aims Losartan potassium-laden pegylated nanocubic vesicles (LP-NCVs-PEG) have an
intriguing kidney-targeted nanoplatform for acute renal injury via blocking apoptosis and …

Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD

ZS Chen, M Ou, S Taylor, R Dafinca, SI Peng… - Nature …, 2023 - nature.com
The GGGGCC hexanucleotide repeat expansion mutation in the chromosome 9 open
reading frame 72 (C9orf72) gene is a major genetic cause of amyotrophic lateral sclerosis …

Therapeutic efficacy of Genistein in activation of neuronal AC/cAMP/CREB/PKA and mitochondrial ETC-Complex pathways in experimental model of autism: Evidence …

S Mehan, A Kumar, T Sharma, Z Khan, A Tiwari… - Brain Research, 2025 - Elsevier
Autism is a complex neurodevelopmental condition characterized by repetitive behaviors,
impaired social communication, and various associated conditions such as depression and …

Developmental pathways linked to the vulnerability of adult midbrain dopaminergic neurons to neurodegeneration

N Prakash - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
The degeneration of dopaminergic and other neurons in the aging brain is considered a
process starting well beyond the infantile and juvenile period. In contrast to other dopamine …

Dual-stimuli-responsive nanoparticles for the co-delivery of small molecules to promote neural differentiation of human iPSCs

JH You, NY Kim, YY Choi, HW Choi, BG Chung - Nanoscale, 2025 - pubs.rsc.org
The differentiation of human induced pluripotent stem cells (hiPSCs) into neural progenitor
cells (NPCs) is a promising approach for the treatment of neurodegenerative diseases and …