[HTML][HTML] Regulation of filaggrin, loricrin, and involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: pathogenic implications in atopic dermatitis

M Furue - International journal of molecular sciences, 2020 - mdpi.com
Atopic dermatitis (AD) is an eczematous, pruritic skin disorder with extensive barrier
dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction …

Environmental stressors on skin aging. Mechanistic insights

C Parrado, S Mercado-Saenz, A Perez-Davo… - Frontiers in …, 2019 - frontiersin.org
The skin is the main barrier that protects us against environmental stressors (physical,
chemical, and biological). These stressors, combined with internal factors, are responsible …

Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases

KE Kim, D Cho, HJ Park - Life sciences, 2016 - Elsevier
Environmental air pollution encompasses various particulate matters (PMs). The increased
ambient PM from industrialization and urbanization is highly associated with morbidity and …

[HTML][HTML] Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance

AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

Environmental air pollutants affecting skin functions with systemic implications

G Bocheva, RM Slominski, AT Slominski - International journal of …, 2023 - mdpi.com
The increase in air pollution worldwide represents an environmental risk factor that has
global implications for the health of humans worldwide. The skin of billions of people is …

The impact of airborne pollution on skin

E Araviiskaia, E Berardesca, T Bieber… - Journal of the …, 2019 - Wiley Online Library
Indoor and outdoor airborne pollutants modify our environment and represent a growing
threat to human health worldwide. Airborne pollution effects on respiratory and cardiac …

Aryl hydrocarbon receptor in atopic dermatitis and psoriasis

M Furue, A Hashimoto-Hachiya, G Tsuji - International journal of …, 2019 - mdpi.com
The aryl hydrocarbon receptor (AHR)/AHR-nuclear translocator (ARNT) system is a sensitive
sensor for small molecular, xenobiotic chemicals of exogenous and endogenous origin …

Diesel exhaust: current knowledge of adverse effects and underlying cellular mechanisms

S Steiner, C Bisig, A Petri-Fink… - Archives of …, 2016 - Springer
Diesel engine emissions are among the most prevalent anthropogenic pollutants worldwide,
and with the growing popularity of diesel-fueled engines in the private transportation sector …

[HTML][HTML] Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation

CJG Pinto, MÁ Ávila-Gálvez, Y Lian, P Moura-Alves… - Redox Biology, 2023 - Elsevier
Abstract The Aryl Hydrocarbon Receptor (AHR) is a ligand-dependent transcription factor
able to control complex transcriptional processes in several cell types, which has been …

[HTML][HTML] Air pollution and skin diseases: A comprehensive evaluation of the associated mechanism

X Gu, Z Li, J Su - Ecotoxicology and Environmental Safety, 2024 - Elsevier
Air pollutants deteriorate the survival environment and endanger human health around the
world. A large number of studies have confirmed that air pollution jeopardizes multiple …