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[HTML][HTML] Regulation of filaggrin, loricrin, and involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: pathogenic implications in atopic dermatitis
M Furue - International journal of molecular sciences, 2020 - mdpi.com
Atopic dermatitis (AD) is an eczematous, pruritic skin disorder with extensive barrier
dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction …
dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction …
Environmental stressors on skin aging. Mechanistic insights
C Parrado, S Mercado-Saenz, A Perez-Davo… - Frontiers in …, 2019 - frontiersin.org
The skin is the main barrier that protects us against environmental stressors (physical,
chemical, and biological). These stressors, combined with internal factors, are responsible …
chemical, and biological). These stressors, combined with internal factors, are responsible …
Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases
KE Kim, D Cho, HJ Park - Life sciences, 2016 - Elsevier
Environmental air pollution encompasses various particulate matters (PMs). The increased
ambient PM from industrialization and urbanization is highly associated with morbidity and …
ambient PM from industrialization and urbanization is highly associated with morbidity and …
[HTML][HTML] Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance
AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …
Environmental air pollutants affecting skin functions with systemic implications
The increase in air pollution worldwide represents an environmental risk factor that has
global implications for the health of humans worldwide. The skin of billions of people is …
global implications for the health of humans worldwide. The skin of billions of people is …
The impact of airborne pollution on skin
E Araviiskaia, E Berardesca, T Bieber… - Journal of the …, 2019 - Wiley Online Library
Indoor and outdoor airborne pollutants modify our environment and represent a growing
threat to human health worldwide. Airborne pollution effects on respiratory and cardiac …
threat to human health worldwide. Airborne pollution effects on respiratory and cardiac …
Aryl hydrocarbon receptor in atopic dermatitis and psoriasis
M Furue, A Hashimoto-Hachiya, G Tsuji - International journal of …, 2019 - mdpi.com
The aryl hydrocarbon receptor (AHR)/AHR-nuclear translocator (ARNT) system is a sensitive
sensor for small molecular, xenobiotic chemicals of exogenous and endogenous origin …
sensor for small molecular, xenobiotic chemicals of exogenous and endogenous origin …
Diesel exhaust: current knowledge of adverse effects and underlying cellular mechanisms
S Steiner, C Bisig, A Petri-Fink… - Archives of …, 2016 - Springer
Diesel engine emissions are among the most prevalent anthropogenic pollutants worldwide,
and with the growing popularity of diesel-fueled engines in the private transportation sector …
and with the growing popularity of diesel-fueled engines in the private transportation sector …
[HTML][HTML] Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation
CJG Pinto, MÁ Ávila-Gálvez, Y Lian, P Moura-Alves… - Redox Biology, 2023 - Elsevier
Abstract The Aryl Hydrocarbon Receptor (AHR) is a ligand-dependent transcription factor
able to control complex transcriptional processes in several cell types, which has been …
able to control complex transcriptional processes in several cell types, which has been …
[HTML][HTML] Air pollution and skin diseases: A comprehensive evaluation of the associated mechanism
X Gu, Z Li, J Su - Ecotoxicology and Environmental Safety, 2024 - Elsevier
Air pollutants deteriorate the survival environment and endanger human health around the
world. A large number of studies have confirmed that air pollution jeopardizes multiple …
world. A large number of studies have confirmed that air pollution jeopardizes multiple …