Beyond latent and active tuberculosis: a sco** review of conceptual frameworks
There is growing recognition that tuberculosis (TB) infection and disease exists as a
spectrum of states beyond the current binary classification of latent and active TB. Our aim …
spectrum of states beyond the current binary classification of latent and active TB. Our aim …
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise
The current active–latent paradigm of tuberculosis largely neglects the documented
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
Quantifying progression and regression across the spectrum of pulmonary tuberculosis: a data synthesis study
Background Prevalence surveys show a substantial burden of subclinical (asymptomatic but
infectious) tuberculosis, from which individuals can progress, regress, or even persist in a …
infectious) tuberculosis, from which individuals can progress, regress, or even persist in a …
Prevalence of subclinical pulmonary tuberculosis in adults in community settings: an individual participant data meta-analysis
L Stuck, E Klinkenberg, NA Ali… - The Lancet Infectious …, 2024 - thelancet.com
Background Subclinical pulmonary tuberculosis, which presents without recognisable
symptoms, is frequently detected in community screening. However, the disease category is …
symptoms, is frequently detected in community screening. However, the disease category is …
[HTML][HTML] A mathematical analysis of the two-strain tuberculosis model dynamics with exogenous re-infection
The rise of drug resistance has become a major obstacle in treating tuberculosis (TB),
significantly contributing to the increasing disease burden. Therefore, it is essential to study …
significantly contributing to the increasing disease burden. Therefore, it is essential to study …
Immunopathology in human tuberculosis
Mycobacterium tuberculosis (M. tb) is a bacterial pathogen that has evolved in humans, and
its interactions with the host are complex and best studied in humans. Myriad immune …
its interactions with the host are complex and best studied in humans. Myriad immune …
Implications of subclinical tuberculosis for vaccine trial design and global effect
GJ Churchyard, RMGJ Houben, K Fielding… - The Lancet …, 2024 - thelancet.com
Tuberculosis is a leading cause of death from an infectious agent globally. Infectious
subclinical tuberculosis accounts for almost half of all tuberculosis cases in national …
subclinical tuberculosis accounts for almost half of all tuberculosis cases in national …
International consensus classification of early tuberculosis states to guide research for improved care and prevention: A Delphi exercise
AK Coussens, SMA Zaidi, BA Allwood… - The Lancet …, 2024 - pmc.ncbi.nlm.nih.gov
The current active/latent paradigm of tuberculosis (TB) largely neglects the documented
spectrum of disease. Lack of consistency on definitions, terminology and diagnostic criteria …
spectrum of disease. Lack of consistency on definitions, terminology and diagnostic criteria …
Tuberculosis in infertility and in vitro fertilization-embryo transfer
X Gai, H Chi, R Li, Y Sun - Chinese Medical Journal, 2024 - mednexus.org
Tuberculosis (TB) is a prominent infectious disease globally that imposes a substantial
health burden. Genital TB (GTB), an extrapulmonary manifestation, leads to complications …
health burden. Genital TB (GTB), an extrapulmonary manifestation, leads to complications …
Reevaluating progression and pathways following Mycobacterium tuberculosis infection within the spectrum of tuberculosis
Traditional understanding of the risk of progression from Mycobacterium tuberculosis (Mtb)
infection to tuberculosis (TB) overlooks diverse presentations across a spectrum of disease …
infection to tuberculosis (TB) overlooks diverse presentations across a spectrum of disease …