Systematic studies of the cancer genome have exploded in recent years. These studies
have revealed scores of new cancer genes, including many in processes not previously …

Studies using dogs provide an ideal solution to the gap in animal models for natural disease
and translational medicine. This is evidenced by approximately 400 inherited disorders …

Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Population bottlenecks, inbreeding, and artificial selection can all, in principle, influence
levels of deleterious genetic variation. However, the relative importance of each of these …

The domestic dog is becoming an increasingly valuable model species in medical genetics,
showing particular promise to advance our understanding of cancer and orthopaedic …

This is the first book to collate and synthesize the recent burgeoning primary research
literature on dog behaviour, evolution, and cognition. The author presents a new ecological …

The extraordinary phenotypic diversity of dog breeds has been sculpted by a unique
population history accompanied by selection for novel and desirable traits. Here we perform …

Although considerable progress has been made in understanding the genetic basis of
morphologic traits (for example, body size and coat color) in dogs and wolves, the genetic …

Dogs are the most phenotypically diverse mammalian species, and they possess more
known heritable disorders than any other non-human mammal. Efforts to catalog and …

In recent years Canis familiaris, the domestic dog, has drawn considerable attention as a
system in which to investigate the genetics of disease susceptibility, morphology and …