Antioxidants and human diseases

P Rajendran, N Nandakumar, T Rengarajan… - Clinica chimica acta, 2014 - Elsevier
Oxidative stress plays a pivotal role in the development of human diseases. Reactive
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …

Health-promoting effects of the citrus flavanone hesperidin

C Li, H Schluesener - Critical reviews in food science and nutrition, 2017 - Taylor & Francis
Hesperidin, a member of the flavanone group of flavonoids, can be isolated in large
amounts from the rinds of some citrus species. Considering the wide range of …

[HTML][HTML] Hesperidin and its aglycone hesperetin in breast cancer therapy: A review of recent developments and future prospects

KM Yap, M Sekar, YS Wu, SH Gan, NNIM Rani… - Saudi Journal of …, 2021 - Elsevier
Breast cancer (BC) has high incidence and mortality rates, making it a major global health
issue. BC treatment has been challenging due to the presence of drug resistance and the …

Phytochemistry and bioactivity of Citrus flavonoids: a focus on antioxidant, anti-inflammatory, anticancer and cardiovascular protection activities

L Yi, S Ma, D Ren - Phytochemistry Reviews, 2017 - Springer
Epidemiological studies have suggested an inverse relationship between increased
consumption of fruits and reduced risk of chronic diseases, such as cardiovascular diseases …

Hesperidin from citrus peel waste: extraction and its health implications

MK Samota, M Kaur, M Sharma, V Krishnan… - … Assurance and Safety …, 2023 - mail.qascf.com
Hesperidin is abundantly present as a flavanone glycoside in citrus fruits. The citrus peels,
seeds, pulp, and cell and membrane residues contain a high amount of hesperidin. It has …

[HTML][HTML] Flavonoid-based nanomedicines to target tumor microenvironment

WH Talib, A Abuawad, S Thiab, A Alshweiat… - OpenNano, 2022 - Elsevier
Cancer cells arise and grow in tumor microenvironment which consists of stromal cells and
extracellular matrix. The dynamic interaction between cancer cells and different components …

Hesperidin: advances on resources, biosynthesis pathway, bioavailability, bioactivity, and pharmacology

T Donia, NM Dabbour, SA Loutfy - Handbook of dietary flavonoids, 2023 - Springer
The dietary flavonoid hesperidin is the most vital phytochemical in orange peel and other
citrus species and is of great general interest due to their diverse bioactivity. Very little …

Targeting FBPase is an emerging novel approach for cancer therapy

GM Liu, YM Zhang - Cancer cell international, 2018 - Springer
Cancer is a leading cause of death in both developed and develo** countries. Metabolic
reprogramming is an emerging hallmark of cancer. Glucose homeostasis is reciprocally …

Phytometabolites targeting the Warburg effect in cancer cells: a mechanistic review

M Hasanpourghadi, C Yeng Looi… - Current drug …, 2017 - benthamdirect.com
Phytometabolites are functional elements derived from plants and most of them exhibit
therapeutic characteristics such as anti-cancer, anti-inflammatory and anti-oxidant effects …

Flavonoids for the treatment of breast cancer, present status and future prospective

S Sahoo, P Mohapatra, SK Sahoo - Anti-Cancer Agents in …, 2023 - benthamdirect.com
Breast Cancer is one of the most notorious cancer affecting women globally. Current
therapies available for breast cancer treatment have certain limited efficacy; develop drug …