Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

The platelet response to tissue injury

F Eisinger, J Patzelt, HF Langer - Frontiers in medicine, 2018 - frontiersin.org
In recent years, various studies have increasingly explained platelet functions not only in
their central role as a regulator in cellular hemostasis and coagulation. In fact, there is …

Integrin-specific hydrogels modulate transplanted human bone marrow-derived mesenchymal stem cell survival, engraftment, and reparative activities

AY Clark, KE Martin, JR García, CT Johnson… - Nature …, 2020 - nature.com
Stem cell therapies are limited by poor cell survival and engraftment. A hurdle to the use of
materials for cell delivery is the lack of understanding of material properties that govern …

Mesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010–2015)

A Singh, A Singh, D Sen - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem cells have been used for cardiovascular regenerative therapy for
decades. These cells have been established as one of the potential therapeutic agents …

Platelets in tissue repair: control of apoptosis and interactions with regenerative cells

M Gawaz, S Vogel - Blood, The Journal of the American Society …, 2013 - ashpublications.org
Besides mediating primary hemostasis and thrombosis, platelets play a critical role in tissue
repair and regeneration. They regulate fundamental mechanisms involved in the healing …

Platelets and immune responses during thromboinflammation

M Mezger, H Nording, R Sauter, T Graf… - Frontiers in …, 2019 - frontiersin.org
Besides mediating hemostatic functions, platelets are increasingly recognized as important
players of inflammation. Data from experiments in mice and men revealed various …

Therapeutic potential of adult bone marrow‐derived mesenchymal stem cells in diseases of the skeleton

D Chanda, S Kumar… - Journal of cellular …, 2010 - Wiley Online Library
Mesenchymal stem cells (MSCs) are the most popular among the adult stem cells in tissue
engineering and regenerative medicine. Since their discovery and functional …

The dual role of mesenchymal stem cells in apoptosis regulation

Z Chen, X ** new methods to deliver cells to the injured tissue is a critical factor
in translating cell therapeutics research into clinical use; therefore, there is a need for …

High targeted migration of human mesenchymal stem cells grown in hypoxia is associated with enhanced activation of RhoA

G Vertelov, L Kharazi, MG Muralidhar, G Sanati… - Stem cell research & …, 2013 - Springer
Introduction A feature which makes stem cells promising candidates for cell therapy is their
ability to migrate effectively into damaged or diseased tissues. Recent reports demonstrated …