Significance: Chronic wounds affect millions of patients worldwide, placing a huge burden
on health care resources. Although significant progress has been made in the development …

Type 2 diabetes mellitus (T2DM) causes peripheral vascular disease because of which
several blood-borne factors, including vital nutrients fail to reach the affected tissue. Tissue …

Tissue injury to skin diminishes miR-200b in dermal fibroblasts. Fibroblasts are widely
reported to directly reprogram into endothelial-like cells and we hypothesized that miR-200b …

Microvascular networks play key roles in oxygen transport and nutrient delivery to meet the
varied and dynamic metabolic needs of different tissues throughout the body, and their …

In this work we introduce a modified form of laser speckle imaging (LSI) referred to as affixed
transmission speckle analysis (ATSA) that uses a single coherent light source to probe two …

Laser speckle contrast imaging of the microcirculatory bed of the pancreas is performed,
which allows its condition to be assessed and thereby is an additional valuable tool for …

Objective: To enable a real-time surgical guidance system that simultaneously monitors
blood vessel perfusion, oxygen saturation, thrombosis, and tissue recovery by combining …

Objective: Hydrolyzed collagen-based matrices are widely used as wound care dressings.
Information on the mechanism of action of such dressings is scanty. The objective of this …

Non-invasive, repeated interrogation of the same wound is necessary to understand the
tissue repair continuum. In this work, we sought to test the significance of non-invasive high …

Laser speckle imaging (LSI) is a well-known and useful approach for the non-invasive
visualization of flows and microcirculation localized in turbid scattering media, including …