Biomimetic peptide self-assembly for functional materials

A Levin, TA Hakala, L Schnaider… - Nature Reviews …, 2020 - nature.com
Natural biomolecular systems have evolved to form a rich variety of supramolecular
materials and machinery fundamental to cellular function. The assembly of these structures …

Nanoprobe-based molecular imaging for tumor stratification

X Ma, M Mao, J He, C Liang, HY **e - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018 - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

Self-assembled peptide drug delivery systems

J Yang, HW An, H Wang - ACS Applied Bio Materials, 2020 - ACS Publications
Over the past several decades, rapid advances have been made in the application of
nanomaterials in the biomedical field including bioimaging and drug delivery. Owing to the …

Microenvironment‐induced in situ self‐assembly of polymer–peptide conjugates that attack solid tumors deeply

Y Cong, L Ji, YJ Gao, FH Liu, DB Cheng… - Angewandte …, 2019 - Wiley Online Library
In cancer treatment, the unsatisfactory solid‐tumor penetration of nanomaterials limits their
therapeutic efficacy. We employed an in vivo self‐assembly strategy and designed polymer …

ROS scavenging biopolymers for anti‐inflammatory diseases: classification and formulation

J Zhang, Y Fu, P Yang, X Liu, Y Li… - Advanced Materials …, 2020 - Wiley Online Library
Reactive oxygen species (ROS), the byproducts of aerobic metabolism, is a class of crucial
molecules in physiological processes, nevertheless, would induce a series of inflammatory …

Design of polymeric carriers for intracellular peptide delivery in oncology applications

S Lv, M Sylvestre, AN Prossnitz, LF Yang… - Chemical …, 2021 - ACS Publications
In recent decades, peptides, which can possess high potency, excellent selectivity, and low
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …

Tumor microenvironment‐responsive dual drug dimer‐loaded pegylated bilirubin nanoparticles for improved drug delivery and enhanced immune‐chemotherapy of …

X Yang, C Hu, F Tong, R Liu, Y Zhou… - Advanced Functional …, 2019 - Wiley Online Library
The application of combinational therapy makes up for the limitation of monotherapy and
achieves superior treatment against cancer. However, the combinational therapy remains …

Self-motivated supramolecular combination chemotherapy for overcoming drug resistance based on acid-activated competition of host–guest interactions

H Wang, H Wu, Y Yi, KF Xue, JF Xu, H Wang… - CCS …, 2021 - chinesechemsoc.org
In this work, we propose a nanoparticle-based strategy of self-motivated supramolecular
combination chemotherapy that carries drugs stably and releases them actively in the acidic …

Protein-mimetic self-assembly with synthetic macromolecules

MH Barbee, ZM Wright, BP Allen, HF Taylor… - …, 2021 - ACS Publications
Protein-mimetic amphiphiles have significant promise as a platform to access the complex
functions of natural biological materials and incorporate the tunability and environmental …